Synthesis, X-Rays Analysis, Docking Study and Cholinesterase Inhibition Activity of 2,3-dihydroquinazolin-4(1H)-one Derivatives [PDF]
In search of potent cholinesterase inhibitors, we have carried out the synthesis and biologically evaluation of various benzaldehyde based 2,3-dihydroquinazolin-4(1H)-one derivatives.
Muhammad Sarfraz+3 more
doaj
Reversible cholinesterase inhibitors as pretreatment for exposure to organophosphates. A review
Organophosphorus compounds (OPCs), inhibitors of acetylcholinesterase (AChE), are useful agents as pesticides, but also represent a serious health hazard.
D. Lorke, G. Petroianu
semanticscholar +1 more source
Potentiation Between Cholinesterase Inhibitors.
SummaryOrganic phosphate insecticides EPN, malathion, chlorothion and phostex, in all possible paired combinations administered simultaneously to mice showed potentiation in their oral toxicities. Some potentiation was observed even when EPN was given 24 hours before malathion.
J. M. Coon, Philip Rosenberg
openaire +3 more sources
Exploring the bio‐functional potential of polysaccharides from Morchella esculenta: A mini review
Abstract Polysaccharides, natural polymers of monosaccharides, exhibit diverse biological activities due to their molecular structures and functional properties. Morchella esculenta, a precious edible mushroom with higher market value, is also rich in polysaccharides (MEP) and holds potential as a bioactive compound with therapeutic and functional food
Shiva Bakshi, Vinod Kumar Paswan
wiley +1 more source
Progress of non‐motor symptoms in early‐onset Parkinson's disease
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang+5 more
wiley +1 more source
Impact of amyloid PET in the clinical care of veterans in a tertiary memory disorders clinic
Introduction We aimed to characterize the clinical impact of amyloid PET (APET) in a veteran population with cognitive decline by comparing differences in management between those who did and did not have an APET.
Ana Laura Vives‐Rodriguez+8 more
doaj +1 more source
Pharmacokinetics and Molecular Docking studies of Plant-Derived Natural Compounds to Exploring Potential Anti-Alzheimer Activity [PDF]
Alzheimer disease (AD) is the leading cause of dementia, accounts for 60 to 80 percent cases. Two main factors called beta amyloid plaques and tangles are prime suspects in damaging and killing nerve cells. However, oxidative stress, the process which produces free radicals in cells, is believed to promote its progression to the extent that it may ...
arxiv
Clinical Signs of Poisoning with Pyrethroid and Cholinesterase Inhibitors
Background: Due to the similarities between clinical signs of toxicity with pyrethroids and cholinesterase inhibitors, if the mistake between these two was made and the patient was treatment with atropine, severe atropine poisoning and even death could ...
Farzad Gheshlaghi, Zohreh Sedighinia
doaj
Chemical principles of instability and self-organization in reacting and diffusive systems [PDF]
How patterns and structures undergo symmetry breaking and self-organize within biological systems from initially homogeneous states is a key issue for biological development. The activator-inhibitor (AI) mechanism, derived from reaction-diffusion (RD) models, has been widely believed to be the elementary mechanism for biological pattern formation. This
arxiv
A novel family of cinnamic acid derivatives has been developed to be multifunctional cholinesterase inhibitors against AD by fusing N-benzyl pyridinium moiety and different substituted cinnamic acids.
Jinshuai Lan+6 more
semanticscholar +1 more source