Results 51 to 60 of about 41,567 (239)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase

Chemistry Central Journal, 2012
Background Alzheimer’s disease (AD) is a neurologically degenerative disorder that affects more than 20 million people worldwide. The selective butyrylcholinesterase (BChE) inhibitors and bivalent cholinesterase (ChE) inhibitors represent new treatments ...
Wang Yue-Hu, Wan Qin-Li, Gu Cheng-Ding, Luo Huai-Rong, Long Chun-Lin   +4 more
doaj   +1 more source

Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study

BMC Geriatrics, 2022
Background Anticholinergic medications are drugs that block cholinergic transmission, either as their primary therapeutic action or as a secondary effect.
Annabelle Hook, Jessica L. Randall, Carla M. Grubb, Natalie Ellis, Jack Wellington, Aayushi Hemmad, Agisilaos Zerdelis, Andrew R. D. Winnett, Benjamin D. W. Geers, Bethany Sykes, Charlotte N. Auty, Cecilia Vinchenzo, Christiane E. Thorburn, Daniella Asogbon, Emily Granger, Heather Boagey, Juliet Raphael, Kajal Patel, Kartik Bhargava, Mary-Kate M. Dolley, Matthew J. Maden, Mehdin M. Shah, Qao M. Lee, Ratnaraj Vaidya, Simran Sehdev, Sneha Barai, Sophie Roche, Uzair Khalid, David A. Codling, Judith R. Harrison   +29 more
doaj   +1 more source

Potentiation Between Cholinesterase Inhibitors.

Experimental Biology and Medicine, 1958
SummaryOrganic phosphate insecticides EPN, malathion, chlorothion and phostex, in all possible paired combinations administered simultaneously to mice showed potentiation in their oral toxicities. Some potentiation was observed even when EPN was given 24 hours before malathion.
P, ROSENBERG, J M, COON
openaire   +2 more sources

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca, Gianmauro Palombelli, Nicola Vanacore, Rossella Canese   +3 more
wiley   +1 more source

Characterization of binding of antipsychotics to muscarinic receptors using mouse cerebral cortex

Journal of Pharmacological Sciences, 2019
Antipsychotics are often the first-line treatment for behavioral and psychological symptoms of dementia. However, the potential anticholinergic effects of antipsychotics could counteract the therapeutic effects of cholinesterase inhibitors used to treat ...
Keisuke Obara, Saki Horiguchi, Toma Shimada, Takumi Ikarashi, Fumiko Yamaki, Kazuhiro Matsuo, Takashi Yoshio, Yoshio Tanaka   +7 more
doaj   +1 more source

Association between specialized nutrition support and 90‐day mortality relative to standard of care in malnourished adults with decompensated cirrhosis: A retrospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Malnutrition is common among patients with decompensated liver cirrhosis and linked to poor prognosis. Guidelines recommend intensified nutrition support e.g. parenteral nutrition, but evidence regarding safety and effectiveness is scarce. We aimed to investigate the impact of nutrition support, specifically parenteral nutrition, on
Katharina L. Hupa‐Breier, Laura Buttler, Claudia Seipt, Andrea Markowski, Marie Griemsmann, Tammo L. Tergast, Birgit Kaufmann, Hannah Rieland, Heiner Wedemeyer, Benjamin Maasoumy, Andrea Schneider   +10 more
wiley   +1 more source

CHOLINESTERASE INHIBITORS IN THE TREATMENT OF DEMENTIA ALZHEIMER’S

e-Jurnal Medika Udayana, 2013
Dementia is the loss of intellectual abilities which include decreased ability to think, remember,understand, calculate, concentrate, and find the right words. The causes of dementia areAlzheimer’s, vascular dementia, alcohol.
Prameidya Primaniar S
doaj  

Difficulties in Diagnosing a Case of Myasthenia Crisis

Journal of Clinical and Biomedical Sciences, 2020
A 26 year old, female presented to EMD in severe respiratory distress. Patient had history of breathlessness since past one month with h/o intrauterine death 1month back .On further investigation it was found that anti acetylcholine receptor ...
Atishaya G V, Prabhakar K, Anitha A, Jithendra Chaitanya   +3 more
doaj   +1 more source

Antihypertensive treatment in people with dementia [PDF]

, 2014
Introduction The range and magnitude of potential benefits and harms of antihypertensive treatment in people with dementia has not been previously established.
Andersson, Asada, Ban, Beishon, Bliwise, Bolbrinker, Bradley, Chow, Duerden, Eriksson, Eriksson, Giron, Graham, Grant, Gribbin, Grossberg, Guasti, Herrmann, Iver, John Gladman, Kehoe, Kennelly, Luijendijk, Meade, Mehrabian, Musini, Nelson, Newman, Novak, Ownby, Pantoni, Pantoni, Pantoni, Pariente, Pellfolk, Perlmuter, Peskind, Pip Logan, Probstfield, Ridgeway, Rowan Harwood, Rozzini, Ruby, Shah, Shankle, Simon Conroy, Sourdet, Suzuki, Tavassoli, Van Doorn, Veronika van der Wardt, Wang, Weiler, Welsh, Wilson, Wiysonge, Woolcott, Wright, Ziegler   +58 more
core   +2 more sources