Results 71 to 80 of about 25,099 (263)
Spectrophotometric determination of cholinesterase activity using carbamate inhibitors [PDF]
, 2017 Charles University, Faculty o Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Student: Ondřej Keresteš Supervisor: PharmDr. Marta Kučerová, Ph.D. Consultant: pplk. prof. RNDr.
Keresteš, Ondřej
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Coumarins: Auspicious Cholinesterase and Monoamine Oxidase Inhibitors
, 2015 Cholinesterase inhibition is the only current validated target in clinics in the treatment of Alzheimer's disease (AD). Therefore, there is continuous interest in the development and discovery of novel cholinesterase inhibitory molecules.
Gulcan, H. Ozan, ERDOĞAN ORHAN, İLKAY
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Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, EarlyView.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Cholinesterase inhibitors from botanicals
Pharmacognosy Reviews, 2013 Alzheimer's disease (AD) is a progressive neurodegenerative disease, wherein a progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased concentration of the neurotransmitter, acetylcholine (ACh), appears to be critical element in the development of dementia, and the most appropriate therapeutic approach to treat AD and ...
Ahmed, Faiyaz +3 more
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Diagnostic Value of Bedside Eye Movement Examination in Movement Disorders
Movement Disorders Clinical Practice, EarlyView.
Eloísa Bittencurt Thomaz de Assis +4 more
wiley +1 more source
Insect Molecular Biology, EarlyView.Aedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Ivan Drahun +3 more
wiley +1 more source
Rational Design of Cholinesterase Inhibitors
, 2000 With the collaboration of the most distinguished scholars in this field Professor Giacobini has put together a publication which will convey present knowledge in the field of molecular biology and genetics, biochemistry, cell biology, pharmacology and ...
FILOCAMO, Luigi, BRUFANI, Mario
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Use of Inhibitors in Cholinesterase Histochemistry [PDF]
Nature, 1965 PRESENT-DAY histochemical methods for demonstrating cholinesterases require the use of inhibitors in order to distinguish between acetyl- (that is, true, or specific) cholinesterase (AChE) and butyryl- (non-specific) cholinesterase (ChE). The histochemical technique determines AChE and ChE together, so that if either enzyme is inhibited without the ...
openaire +2 more sources
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Over 50% of persons living with dementia (PLWD) and their care partners (dyads) visit the emergency department (ED) every year. In the ED, healthcare professionals face complex challenges managing acute issues and symptoms of Alzheimer's disease and Alzheimer's disease–related dementias without provider training or in‐ED structures to ensure a
Afshana Hoque +59 more
wiley +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT More than 6 million persons living with dementia (PLWD) in the United States rely on the emergency department (ED) for unscheduled care, with up to half discharged home after treatment. The ED‐to‐home transition poses significant challenges for PLWD and their care partners (referred to as “dyads”), contributing to high rates of ED revisits and
Meghan Jenkins Morales +54 more
wiley +1 more source