Results 81 to 90 of about 41,567 (239)

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadary, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Upper gastrointestinal bleed associated with cholinesterase inhibitor use [PDF]

, 2015
An 86-year-old man was admitted with a 3-day history of melaena and syncope. He was haemodynamically compromised and anaemic on presentation. His only medical history was mild Alzheimer's disease diagnosed 6 months prior. For this, he was on donepezil, a
Kok, Khoon-Sheng, Loke, Yoon, Southgate, Jo   +2 more
core   +1 more source

Diagnostic Value of Bedside Eye Movement Examination in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Eloísa Bittencurt Thomaz de Assis, Paula Martínez Ruiz, Cristina Acosta Gudiel, Hüseyin Nezih Özdemir, Diego Kaski   +4 more
wiley   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

British Journal of Pharmacology, EarlyView.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau, Chloé Veront, Alexandra Cremades, Priscilla Martin, Remi Gojard, Nicolas Galland, Emiliane Taillebois, Dieudonnée Togbé, Jean‐Yves Le Questel, Steeve H. Thany   +9 more
wiley   +1 more source

Unraveling the impact of common medications on biomarker patterns in Alzheimer's disease and mild cognitive impairment

Journal of Alzheimer's Disease Reports
Background The aging global population faces significant challenges from Alzheimer's disease (AD). Metabolomics offers a non-invasive, cost-effective diagnostic alternative.
Kaitlyn Paez, Claire Kopachik, Ali Yilmaz, Sangeetha Vishweswaraiah, Nadia Ashrafi, Nazia Saiyed, Nicolette Monacelli, Ieva Kerseviciute, Juozas Gordevicius, Stacey Ruff, Amita Pai, Imam Khaled, Michael E Maddens, Stewart F Graham   +13 more
doaj   +1 more source

Relationship between hearing function and myasthenia gravis: a contemporary review [PDF]

, 2016
There is increasing evidence of a connection between hearing function and myasthenia gravis (MG). Studies of the pathophysiological basis of this relationship suggest that acetylcholine receptors (AChRs) on outer hair cells (OHCs) play a central role. In
ALTISSIMI, Giancarlo, CIANFRONE, Giancarlo, DI STADIO, Arianna, MAZZEI, FILIPPO, RALLI, MASSIMO, TURCHETTA, Rosaria   +5 more
core   +1 more source

Adaptation of DETECT for Use in Home‐Based Primary Care: Clinician Perspectives

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Elder mistreatment (EM) is pervasive yet under‐identified. The Detection of Elder abuse Through Emergency Care Technicians (DETECT) tool was developed to improve EM identification and reporting among emergency medical technicians. This study explores clinician perspectives on adapting DETECT for use in home‐based primary care (HBPC).
Kristin Lees Haggerty, Randi Campetti, Olanike Ojelabi, Jason Burnett, Melvin Livingston, Carolyn Pickering, Rania Abdelkhaleq, Faith D. Atai, Thomas K. M. Cudjoe, Deborah G. Freeland, Julia Hiner, Maria Yefimova, Brad Cannell   +12 more
wiley   +1 more source

Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis. [PDF]

, 2015
OBJECTIVE: The authors examined research on effects, costs, and patient and caregiver views of pharmacological management strategies for Lewy body dementia.
Cambridge, Victoria, Lafortune, Louise, Mak, Elijah, Mason, James, McKeith, Ian, Mioshi, Eneida, O'Brien, John T, Stinton, Chris, Taylor, John-Paul, Thomas, Alan   +9 more
core   +2 more sources

Cholinesterase inhibitors for Parkinson’s disease-related visual hallucinations unresponsive to atypical antipsychotics

Archives of Medical Science, 2007
Introduction: Considering lack of accepted guideline in cases of Parkinson’s disease-related visual hallucinations with poor response or intolerance to antipsychotics, and their possible cholinergic pathogenesis, the trial with cholinesterase inhibitors ...
Tomasz Sobow
doaj