Results 61 to 70 of about 411 (95)

Hemoperfusion in combination with hemofiltration for acute severe organophosphorus pesticide poisoning: A systematic review and meta-analysis. [PDF]

J Res Med Sci, 2022
Zhang M, Zhang W, Zhao S, Tian X, Fu G, Wang B.   +5 more
europepmc   +1 more source

Synthesis and Evaluation of Halogenated Pralidoximes in Reactivation of Organophosphate-Inhibited Cholinesterases. [PDF]

ACS Med Chem Lett
Knittelova K, Prchalova E, Fuchsova A, Andrys R, Kohoutova Z, Rademacherova S, Prchal L, Musilek K, Malinak D.   +8 more
europepmc   +1 more source

Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice. [PDF]

Molecules, 2022
Wei Z, Zhang X, Nie H, Yao L, Liu Y, Zheng Z, Ouyang Q.   +6 more
europepmc   +1 more source

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase. [PDF]

Chemistry, 2022
Lindgren C, Forsgren N, Hoster N, Akfur C, Artursson E, Edvinsson L, Svensson R, Worek F, Ekström F, Linusson A.   +9 more
europepmc   +1 more source

Accelerating countermeasure candidate discovery for A-series chemical warfare agent exposure. [PDF]

Proc Natl Acad Sci U S A
Morato NM, Mason KE, Corzett TH, Valdez CA, Alfaro TM, Hok S, Cooks RG, Mayer BP.   +7 more
europepmc   +1 more source

Nanodiamond mediated delivery of pyridinium oxime antidotes to central nervous system for potential treatment of exposure to nerve agents. [PDF]

Chem Biol Interact
Bondar D, Smirnova O, Nagappa NM, Heinmaa I, Soukup O, Kobrlova T, Opravil J, Hrabinova M, Jun D, Starkov P, Spuul P, Kuča K, Mochalin VN, Karpichev Y.   +13 more
europepmc   +1 more source

Structure-guided modification of a lead cholinesterase-targeting oxime to improve peripheral site binding. [PDF]

Arh Hig Rada Toksikol
Maraković N, Probst N, Čadež T, Zandona A.   +3 more
europepmc   +1 more source

Advancements in bioscavenger mediated detoxification of organophosphorus poisoning. [PDF]

Toxicol Res (Camb)
Li H, Lu C, Liu Z, Xiang F, Liu B, Wang H, Chang J, Pan L, Chen Y, Chen J.   +9 more
europepmc   +1 more source

A Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate. [PDF]

Int J Nanomedicine
Pirollo KF, Moghe M, Guan M, Rait AS, Wang A, Kim SS, Chang EH, Harford JB.   +7 more
europepmc   +1 more source

Kinetic and structural evidence for specific DMSO interference with reversible binding of uncharged bis-oximes to hAChE and their reactivation kinetics of OP-hAChE. [PDF]

Chem Biol Interact
Kolić D, Gerlits O, Kucharski M, Gorecki L, Joiner N, Kovalevsky A, Radić Z.   +6 more
europepmc   +1 more source