Results 41 to 50 of about 15,570 (165)
Movement Disorders Clinical Practice, Volume 12, Issue 11, Page 1882-1890, November 2025.Abstract Background Both autonomic dysfunction and low levels of physical activity could contribute to reduced cardiorespiratory fitness in people with Parkinson's disease (PD). However, the interrelationship between these concepts is not well understood.
Kars I. Veldkamp +5 more
wiley +1 more source
Chemical structures of oxime reactivators.
, 2013 Chemical structures of oxime reactivators.
Aastha Jain (491658) +4 more
core +1 more source
Organophosphate Poisoning: Insights From a Case Report of Acute Cholinergic Syndrome
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT Organophosphate (OP) pesticides are widely used in agriculture and can cause acute cholinergic toxicity by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine. A 45‐year‐old male plumber was admitted to the emergency department 4 h after ingesting an unknown quantity of a 50% emulsifiable concentration of ...
Gudisa Bereda
wiley +1 more source
Chemical structures of neutral oxime reactivators.
, 2013 Chemical structures of neutral oxime reactivators.
Aastha Jain (491658) +4 more
core +1 more source
Gene and RNA Editing: Revolutionary Approaches to Treating Diseases
MedComm, Volume 6, Issue 10, October 2025.The image illustrates gene editing technologies: DNA editing using CRISPR–Cas9 and RNA editing via Cas13d, with their clinical applications and ethical risks. DNA editing allows precise gene modifications for conditions like amyotrophic lateral sclerosis [ALS] and Huntington's disease, while RNA editing supports multiplexed modifications.
Jia‐Mei Li +6 more
wiley +1 more source
SmartMat, Volume 6, Issue 5, October 2025.Butyrylcholinesterase (BChE), a key member of the cholinesterase family, plays an indispensable role in neural signal regulation, Alzheimer's disease therapeutic development, metabolic homeostasis, and clinical toxicology diagnostics. This study provides a comprehensive review of existing analytical methodologies for BChE detection, along with their ...
Min Liu +7 more
wiley +1 more source
Midostaurin in daily clinical practice of patients with advanced systemic mastocytosis
British Journal of Haematology, Volume 207, Issue 4, Page 1388-1396, October 2025.Durable responses based on modified Valent, IWG‐MRT‐ECNM and PPR criteria were predominantly dose‐independent, making dose adjustments due to better tolerability more practicable in daily routine. Gradual tapering of midostaurin, prophylactic treatment with antihistamines and corticosteroids and timely initiation of subsequent therapy can prevent a ...
Johannes Lübke +10 more
wiley +1 more source
Movement Disorders Clinical Practice, Volume 12, Issue 8, Page 1173-1180, August 2025.Abstract Background The coexistence of tics with Parkinson's disease (PD) is rare, as they often emerge at different ages, follow different trajectories and involve contrasting pathophysiological mechanisms related to dopamine availability and function in the brain. Cases We present 10 individuals with primary tic disorders who later developed PD.
Tarig Abkur +11 more
wiley +1 more source
The concept of organophosphate-inhibited non-selective cholinesterase reactivators
Nerve agents (NAs) are considered the most dangerous class of chemical warfare agents. They can be accidentally misused in local or mass conflicts by terrorists or other forces.
Jan Korabecny
core +1 more source
Synthesis of bisquaternary asymmetrical reactivators of acetylcholinesterase [PDF]
, 2008 Markéta Komlóová: Synthesis of bisquarternary asymmetrical reactivators of acetylcholinesterase Nine potential bisquaternary reactivators of AChE have been prepared and their reactivation activity against paraoxon or tabun-inhibited enzyme has been ...
Komlóová, Markéta
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