Results 111 to 120 of about 27,370 (335)
ABSTRACT Background Congenital mirror movement disorders (CMMs) are clinically and genetically heterogeneous in human patients. CMMs have not been documented to occur spontaneously in animals. Objective The objective of this work was to document the first case of CMMs spontaneously occurring in Weimaraner dogs and to identify the underlying genetic ...
Cleo Schwarz+11 more
wiley +1 more source
New Multitarget Rivastigmine–Indole Hybrids as Potential Drug Candidates for Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common form of dementia with no cure so far, probably due to the complexity of this multifactorial disease with diverse processes associated with its origin and progress.
Leo Bon+6 more
doaj +1 more source
Synthesis, X-Rays Analysis, Docking Study and Cholinesterase Inhibition Activity of 2,3-dihydroquinazolin-4(1H)-one Derivatives [PDF]
In search of potent cholinesterase inhibitors, we have carried out the synthesis and biologically evaluation of various benzaldehyde based 2,3-dihydroquinazolin-4(1H)-one derivatives.
Muhammad Sarfraz+3 more
doaj
Two selective inhibitors of cholinesterase [PDF]
L. Austin, W.K. Berry
openalex +1 more source
Abstract Background Tremor phase‐locked deep brain stimulation (DBS) has been shown to modulate symptom severity in postural tremor, including essential and dystonic tremor, with less energy than existing systems. Previous studies focused on unilateral stimulation; it remains unknown how tremor asymmetry interacts with stimulation in the context of ...
Shenghong He+16 more
wiley +1 more source
Presence of cholinesterases in Echinococcus granulosus protoscolices
Cholinesterases were detected in protoscolices of Echinococcus granulosus spectrophotometrically and electrophoretically. To characterize these activities as acetylcholinesterases or pseudocholinesterases, BW284C51 and the organophosphate anthelmintic ...
Giménez-Pardo C.+3 more
doaj +1 more source
The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. 3 [PDF]
openalex +1 more source
ABSTRACT Background Resilience factors are crucial in the progression of neurodegenerative diseases. However, it remains unclear whether a genetic predisposition to cognitive reserve influences clinical heterogeneity in the prognosis of Parkinson's disease (PD).
Young Eun Huh+5 more
wiley +1 more source