Results 91 to 100 of about 8,411 (245)

Evolution of animal cholinesterases

, 2016
Cholinesterases emerged from a family of enzymes and proteins with adhesion properties. This family is absent in plants and expanded in multicellular animals [1,2].
Chatonnet, Arnaud, Lenfant, Nicolas, Bourne, Yves, Hotelier, Thierry, Selkirk, Murray E., Marchot, P., Marchot, Pascale   +6 more
core  

Blood Cholinesterases from Washington State Orchard Workers [PDF]

, 2009
Court-ordered monitoring of blood cholinesterases (ChEs) from orchard workers in Washington State is underway. In 2008, the mean red blood cell acetylcholinesterase (AChE, EC 3.1.1.7) activity was 9.65 ± 1.11 μmoles/min/ml (n = 1,793) and the mean serum (
Henderson, John D., John L. Furman, David Michaelson, Furman, John L., Zeller, Bruce E., John D. Henderson, Barry W. Wilson, Bruce E. Zeller, Wilson, Barry W., Michaelson, David   +9 more
core   +1 more source

Genome assembly of Elcysma westwoodi provides insights into host‐plant cyanogenic glucoside detoxification and chemical defence gene evolution

Insect Molecular Biology, EarlyView.
A chromosome‐level genome of Elcysma westwoodi was assembled. The genome encodes 272 detoxification‐related genes. A single‐copy bCAS was retained for cyanide detoxification. CYP405A and CYP332A were recruited into cyanogenic defence evolution. UGT33A retained a conserved GT‐B fold and catalytic domains.
Minyoung Choi, Murtaza Khan, Juil Kim
wiley   +1 more source

Synthesis and evaluation of potential cholinesterases inhibitors

, 2019
This bachelor thesis deals with the synthesis of novel acetylcholinesterase and butyrylcholinesterase inhibitors as potential inhibitors of both cholinesterases.
Vu, Quynh Anh
core   +1 more source

Burden and Risk Factors of CGM‐Detected Hypoglycemia in Older Adults With Type 2 Diabetes

Journal of the American Geriatrics Society, EarlyView.
Among older adults with diabetes using insulin or sulfonylureas, the median time spent in hypoglycemia was 3.4% and ~66% of participants exceeded the target of < 1% time with CGM glucose < 70 mg/dL. ABSTRACT Background Comprehensive data on the burden of biochemical hypoglycemia in older adults with type 2 diabetes are lacking.
Michael Fang, Natalie Rula Daya, Yein Jeon, Justin B. Echouffo‐Tcheugui, B. Gwen Windham, Scott Zeger, Elizabeth Selvin   +6 more
wiley   +1 more source

Resorcinol-, catechol- and saligenin-based bronchodilating β2-agonists as inhibitors of human cholinesterase activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
We investigated the influence of bronchodilating β2-agonists on the activity of human acetylcholinesterase (AChE) and usual, atypical and fluoride-resistant butyrylcholinesterase (BChE). We determined the inhibition potency of racemate and enantiomers of
Anita Bosak, Anamarija Knežević, Ivana Gazić Smilović, Goran Šinko, Zrinka Kovarik   +4 more
doaj   +1 more source

Development of a Video‐Based Decision Aid for Breast Cancer Screening Among Older Women

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Whether to continue breast cancer screening beyond age 74 is uncertain. Decision aids may improve understanding of health information and support informed screening decisions. The goal of this study was to develop a video‐based decision aid for breast cancer screening among older women using patient‐centered design.
Meghan E. Lindsay, Iyanuoluwa Odole, Sadde Mohamed, Claire King, Nancy L. Schoenborn, Mara A. Schonberg, Ilana B. Richman   +6 more
wiley   +1 more source

Structure and Function of Cholinesterases and Related Proteins

, 2013
The Sixth International Meeting on Cholinesterases and Related Proteins, Choli- nesterases '98, was organized by Palmer Taylor and his associates at the University of California-San Diego and convened in La Jolla, California, USA, in March of 1998.
Doctor, Bhupendra P, Taylor, Palmer, Rotundo, Richard L, Quinn, Daniel M, Gentry, Mary Kay   +4 more
core   +4 more sources

An Electronic Health Record “Nudge” to Reduce Antipsychotic Medication Prescribing for Primary Care Patients With Dementia: A Pragmatic RCT

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background We hypothesized that an electronic health record (EHR) alert grounded in behavioral science could reduce new antipsychotic medication prescriptions for older adults with dementia. Methods We conducted a pragmatic clinical trial at a large academic health system, randomizing providers to receive the alert (intervention) or not ...
Catherine A. Sarkisian, Chad Wes Villaflores, Anne M. Walling, Sitaram S. Vangala, Eric M. Cheng, Suzanne Bliven Shu, Ajaya Pillai, Grace Y. Cheng, Noah Goldstein, John Mafi   +9 more
wiley   +1 more source

Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia

Molecules, 2017
Cassia obtusifolia Linn. have been used to improve vision, inflammatory diseases, and as hepatoprotective agents and to promote urination from ancient times.
Srijan Shrestha, Su Hui Seong, Pradeep Paudel, Hyun Ah Jung, Jae Sue Choi   +4 more
doaj   +1 more source