Results 81 to 90 of about 4,982 (202)

Investigating the Antidiabetic Effects of Calotropis procera: Preclinical Assessment

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Calotropis Procera In vitro/Diabetic rodent model Improved β‐cell function, reduced hepatic gluconeogenesis antioxidant activity. ABSTRACT Diabetes mellitus (DM) is a metabolic disease characterized by persistent hyperglycemia, oxidative stress, and inflammation, often leading to severe complications.
Yu‐Cheng Kuo, Musa I. Ajibola, Halimat Y. Lukman, Bashir Lawal, Lung‐Ching Chen, Sheng‐Liang Huang, Olawale David Ajayi, Sunday Amos Onikanni, Saheed Sabiu, Leandro Miranda‐Alves, Hsu‐Shan Huang   +10 more
wiley   +1 more source

Clinical study of butyrylcholinesterase and heparin binding protein as early markers of traumatic inflammation

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background To observe the changes of butyrylcholinesterase (BChE) and heparin binding protein (HBP) in post‐traumatic inflammation, in order to determine whether they can be used as early diagnostic indicators of post‐traumatic inflammation. Methods Injury severity score (ISS) was used to evaluate the severity of trauma.
Huiying Zhang, Hui Liu, Jianguo Wang
wiley   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, Volume 36, Issue 8, Page 887-898, August 2026.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Off‐Label Initiation of Gabapentin and Valproic Acid Among Long‐Stay Nursing Home Residents With and Without Dementia

Journal of the American Geriatrics Society, EarlyView.
Lauren B. Gerlach, Lan Zhang, Ana Montoya, Sarah L. Krein, Andrew R. Zullo, Julie P. W. Bynum, Donovan Maust   +6 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

Influence of N‐Functionalization of Amiridine on the Biological Activity of Its Conjugates as Multitarget Agents for Potential Treatment of Alzheimer's Disease

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
New conjugates of amiridine and salicylimine/amine with an N‐acylalkylene spacer were synthesized. N‐acylation of amiridine conjugates leads to a decrease in their protonation, resulting in a substantial reduction in anticholinesterase activity and relative inability to block Aβ42 self‐aggregation compared to previously studied analogs with an N ...
Galina F. Makhaeva, Tatiana Y. Astakhova, Maria V. Grishchenko, Tatiana S. Shteinberg, Nadezhda V. Kovaleva, Natalia P. Boltneva, Elena V. Rudakova, Pavel G. Pronkin, Elena N. Timokhina, Eugene V. Radchenko, Evgeny V. Shchegolkov, Yanina V. Burgart, Victor I. Saloutin, Valery N. Charushin, Rudy J. Richardson   +14 more
wiley   +1 more source

Single but Not Combined In Vitro Exposure to Bisphenol A and Nanoplastics Affects the Cholinergic Function of the Ascidian Ciona robusta

Journal of Xenobiotics
Nanoplastics are known to represent a threat to marine ecosystems. Their combination with other contaminants of emerging concerns (CECs) may amplify ecotoxic effects, with unknown impacts on marine biodiversity.
Safa Melki, Emma Ferrari, Raja Ben Ahmed, Antonietta Spagnuolo, Ilaria Corsi   +4 more
doaj   +1 more source

Fiziološka uloga i klinički značaj serumske holinesteraze [PDF]

Vojnosanitetski Pregled, 2004
Balkanov Trajan, Konstantinović Slavko
doaj   +1 more source

The cholinesterases

Journal of Biological Chemistry, 1991
openaire   +2 more sources