Results 111 to 120 of about 129,913 (308)

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Chondrocyte ferroptosis contribute to the progression of osteoarthritis

open access: yesJournal of Orthopaedic Translation, 2020
Xudong Yao   +9 more
semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

open access: yesAdvanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang   +10 more
wiley   +1 more source

Voltage-Gated Ion Channels are Involved in the Signaling Pathway of Differentiating Chondrocytes [PDF]

open access: bronze, 2011
Zoltán Varga   +8 more
openalex   +1 more source

Trained Immunity Exacerbates Inflammatory Arthritis Progression via Promoting Synovial Fibroblast Ferroptotic Resistance

open access: yesAdvanced Science, EarlyView.
β‐glucan‐induced trained immunity reprograms macrophages toward hyperinflammation, exacerbating inflammatory arthritis. In a collagen‐induced arthritis model, trained macrophages intensify disease severity and confer ferroptosis resistance in synovial cells via IL‐1β/NAT10‐mediated FSP1 mRNA modification.
Haibo Su   +12 more
wiley   +1 more source

Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation.

open access: yesNew England Journal of Medicine, 1994
M. Brittberg   +5 more
semanticscholar   +1 more source

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