Results 91 to 100 of about 76,519 (202)

Mechanisms Underlying the Stimulation of DUSP10/MKP5 Expression in Chondrocytes by High Molecular Weight Hyaluronic Acid

Biomedicines
Background/Objectives: Previously, we reported that high molecular weight hyaluronic acid (HMW-HA) exerts chondroprotective effects by enhancing dual specificity protein phosphatase 10/mitogen-activated protein kinase (MAPK) phosphatase 5 (DUSP10/MKP5 ...
Wataru Ariyoshi, Jun Takeuchi, Sho Mitsugi, Ayaka Koga, Yoshie Nagai-Yoshioka, Ryota Yamasaki   +5 more
doaj   +1 more source

Chondrocyte death in injured articular cartilage – in vitro evaluation of chondroprotective strategies using confocal laser scanning microscopy [PDF]

, 2011
A reproducible in vitro model of mechanically injured (scalpel cut) articular cartilage was developed in this work utilising bovine and human osteochondral tissue. Using fluorescence-mode confocal laser scanning microscopy (CLSM), the model allowed (1)
Amin, Anish Kiritkumar
core   +1 more source

Mesenchymal Stem Cell and Chondrocyte Fates in a Multishear Microdevice Are Regulated by Yes-Associated Protein

, 2013
Mechanical cues exert considerable influence on the fates of stem cells and terminally differentiated chondrocytes. The elucidation of the interactions between cell fate and mechanical cues in nuclear mechanotransduction will provide new clues to ...
Tian, Kang, Qin, Jianhua, WeiguoZhang, Li, Linan, Zheng, Xifu, Wang, Shouyu, Zhang, Weiguo, Zhong, Weiliang   +7 more
core   +1 more source

β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis. [PDF]

Osteoarthritis (OA) is the most prevalent age-related degenerative disorder, which severely reduces the quality of life of those affected. Whilst management strategies exist, no cures are currently available.
Lucy V. Norling, Austin-Williams, S, Pinto, AL, Hussain, MT, Norling, LV, Mohammed Tayab Hussain, Andreia L. Pinto, Umesh Kumar Dhawan, Wright, TD, Thomas Dudley Wright, Cooper, D, Dianne Cooper, Shani Austin-Williams, Dhawan, UK   +13 more
core   +1 more source

chondrocyte

Citation: 'chondrocyte' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10513 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Single-cell RNA sequencing reveals chondrocyte heterogeneity and fibrocartilage transition in osteonecrosis of the femoral head. [PDF]

iScience
Liu T, Nan K, Dang X, Wang W, Song J.
europepmc   +1 more source

IL-1β as an important mediator of macrophage-chondrocyte crosstalk in pararamosis (rainforest arthritis). [PDF]

Front Immunol
Pohl PC, Zapotoski LNK, Sardinha LR, Villas-Boas IM, Pidde G, Tambourgi DV.   +5 more
europepmc   +1 more source

Emerging molecular mechanisms of the ECM-exosome growth-plate axis in idiopathic short stature. [PDF]

Front Cell Dev Biol
Piao L, Wang H, Zhang Q, Li J, Sun H, Sun R, Li M, Wang Y.   +7 more
europepmc   +1 more source

A biomimetic chondrocyte membrane-camouflaged tFNA nanoplatform for reprogramming the cartilage-synovium axis in osteoarthritis. [PDF]

Mater Today Bio
Zhang Z, Li Y, Ye M, Liu H, Huang Q, Wang X, Shen M, Xu S, Li J.   +8 more
europepmc   +1 more source

Lactate-driven lactylation reprograms chondrocyte fate and joint inflammation in osteoarthritis: linking metabolism with epigenetic regulation. [PDF]

Front Cell Dev Biol
Liu X, Hu K, Bai D.
europepmc   +1 more source