Results 81 to 90 of about 76,519 (202)
Influence of Mechanical Unloading on Articular Chondrocyte Dedifferentiation [PDF]
, 2018 Due to the limited self-repair capacity of articular cartilage, the surgical restoration of defective cartilage remains a major clinical challenge. The cell-based approach, which is known as autologous chondrocyte transplantation (ACT), has limited ...
Egli, Marcel +18 more
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Mechanoelectrical transduction in chondrocytes
Clinical and Experimental Pharmacology and Physiology, 2018 SummaryCartilage tissue lines the joints of mammals, helping to lubricate joint movement and distribute mechanical loads. This tissue is comprised of isolated cells known as chondrocytes which are embedded in an extracellular matrix. Chondrocytes produce and maintain the cartilage by sensing and responding to changing mechanical loads. Mechanosensitive
Servin-Vences, MR +3 more
openaire +3 more sources
Long-term effects of hydrogel properties on human chondrocyte behavior
, 2010 Hydrogels provide a 3-dimensional network for embedded cells and offer promise for cartilage tissue engineering applications. Nature-derived hydrogels, including alginate, have been shown to enhance the chondrocyte phenotype but are variable and not ...
June Evelyn Jeon +13 more
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Cartilage tissue engineering using pre-aggregated human articular chondrocytes [PDF]
, 2008 In this study, we first aimed at determining whether human articular chondrocytes (HAC) proliferate in aggregates in the presence of strong chondrocyte mitogens.
Farhadi, J. +13 more
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Bone & Joint ResearchAims: Osteoarthritis (OA) is the most common chronic pathema of human joints. The pathogenesis is complex, involving physiological and mechanical factors. In previous studies, we found that ferroptosis is intimately related to OA, while the role of Sat1
Jingting Xu +9 more
doaj +1 more source
Enhanced chondrocyte culture and growth on biologically inspired nanofibrous cell culture dishes
, 2016 Garima Bhardwaj,1 Thomas J Webster1,2 1Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: Chondral and ...
Bhardwaj G, Webster TJ
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, 2020 Articular cartilage lesions occur frequently but unfortunately the damaged cartilage has a very limited intrinsic repair capacity. Since the cartilage damage can cause sterile inflammation, the effects of inflammation on cartilage repair should be well ...
Zhu, Yufang +5 more
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Chondrocytes in fracture healing: A review of chondrocyte journey
Chinese Medical JournalAbstract Previous studies have confirmed that chondrocytes are derived from mesenchymal stem cells (MSCs) and mature into hypertrophic chondrocytes during endochondral ossification. This maturation is followed by apoptosis, which induces vascular invasion, cartilage matrix degradation, and osteoblast differentiation.
Tao Zhang +8 more
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ELR+ CXC chemokine signalling in cartilage homeostasis. [PDF]
, 2011 PhDThe production of ELR+ CXC chemokines is widely studied in arthritis and has been postulated to contribute to the inflammatory phenomena that eventually lead to cartilage breakdown.
Sherwood, Joanna
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