Results 61 to 70 of about 97,625 (307)

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]

, 2013
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P, Bader, DL, Chowdhury, TT, Hobbs, AJ, Moyes, AJ, Peake, N, Ramachandran, M, Salter, DM, Su, N   +8 more
core   +3 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Ameliorative Effects of Cardamonin on Monosodium Urate-Induced Gouty Arthritis through Inhibiting NLRP3 Inflammasome Mediation

Medicina, 2021
Background and Objectives: Gouty arthritis is an acute inflammatory response caused by the precipitation of monosodium urate (MSU) crystals in joints. The triggering of MSU leads to increased production of inflammatory cytokines, such as interleukin-1β ...
Chih-Chien Wang, Jeng-Wei Lu, Yi-Jen Peng, Chian-Her Lee, Herng-Sheng Lee, You-Hsiang Chu, Chun-Jung Huang, Yi-Jung Ho, Feng-Cheng Liu, Chia-Chun Wu   +9 more
doaj   +1 more source

Histological features of the distal third metacarpal bone in thoroughbred racehorses, with and without lateral condylar fractures [PDF]

, 2017
A detailed histopathological study of the distal third metacarpal bone of Thoroughbred racehorses was undertaken to characterize lesions observed previously on magnetic resonance imaging (MRI).
Blunden, A.S., Chang, Y.M., Murray, R.C., Parkin, T.D.H., Pinilla, M.J., Tranquille, C.A.   +5 more
core   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Isorhamnetin inhibits mechanical stress-induced chondrocyte apoptosis through activation of the ROS/SRC/FOXO1 signaling pathway

Scientific Reports
Intervertebral disc degeneration (IDD), a chronic degenerative disease, is characterized by pain without a satisfactory therapeutic strategy. Excessive mechanical pressure contributes to the pathological development of IDD by inducing chondrocyte ...
Jinliang Lai, Guoqiang Yin, Fanmao Zhu, Jishang Huang, Xinghua Hu, Lei Liao, Rong Wu, Jiayu Tao, Shuyue Wang, Yang Xiao, Yiming Gu, Shan Li, Jie Zhou, Yadong Yang   +13 more
doaj   +1 more source

Direct Perfusion Improves Redifferentiation of Human Chondrocytes in Fibrin Hydrogel with the Deposition of Cartilage Pericellular Matrix

Applied Sciences, 2021
Articular cartilage has limited potential for self-repair, and cell-based strategies combining scaffolds and chondrocytes are currently used to treat cartilage injuries.
Alexandre Dufour, Frédéric Mallein-Gerin, Emeline Perrier-Groult   +2 more
doaj   +1 more source

Expression and Localization of aquaporin‐1 in Temporomandibular Joint Disc with Internal Derangement [PDF]

, 2012
Background: Internal derangement is the most frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction.
Almeida, Luis Eduardo, Caltabiano, Rosario, Carnazza, Maria Luisa, Galanti, Concetta, Leonardi, Rosalia, Loreto, Carla, Musumeci, Giuseppe, Pannone, Giuseppe   +7 more
core   +2 more sources

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

Advanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu, Mengsi Zhan, Haoyu Huang, Jianhong Wang, Cheng Ni, Xiaojun Zhou, Hannah Küttner, Cong Song, Xiangyang Shi, Andrij Pich   +9 more
wiley   +1 more source

Single-cell RNA-seq analysis reveals the Wnt/Ca2+ signaling pathway with inflammation, apoptosis in nucleus pulposus degeneration

BMC Musculoskeletal Disorders
Background Increasing studies have shown degeneration of nucleus pulposus cells (NPCs) as an critical part of the progression of intervertebral disc degeneration (IVDD).
Peigeng Wang, Zhencong Li, Dongping Ye
doaj   +1 more source