Results 251 to 260 of about 129,913 (308)

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis. [PDF]

Int J Mol Med
Jie L, Zhang Y, Liu J, Fu H, Zhu Z, Huang Z, Shi X, Wang P, Yin S.   +8 more
europepmc   +1 more source

P146 DYNAMIC COMPRESSION OF CHONDROCYTES INDUCES A RHO KINASE-DEPENDENT REORGANIZATION OF THE ACTIN CYTOSKELETON

, 2006
Dominik R. Haudenschild, Brenda Nguyen, Z. Dooley, J. Chen, Yunxian Mak, C. Colwell, Darryl D. D’Lima, Martin Lotz   +7 more
openalex   +1 more source

Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives We propose a non‐destructive laser method that uses controlled thermomechanical action to treat degenerative cartilage changes. The technique aims to reduce pain, offers a minimally invasive option for early‐ to mid‐stage degeneration, and lessens the need for joint replacement.
Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol   +6 more
wiley   +1 more source

Deubiquitinating Enzymes in Osteoarthritis: From Mechanisms to Therapeutic. [PDF]

Orthop Rev (Pavia)
Yuan Z, Chen G, Li Y, Zhao Z, Zhang H.
europepmc   +1 more source

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

Macromolecular Materials and Engineering, EarlyView.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz, Sevda Gursoy, Gulsah Torkay, Shhd Saraj, Louna Karzoun, Alpay Kose, Mert Akin Insel, Ridvan Yildirim, Ayca Bal Ozturk, Ayse Ceren Calikoglu Koyuncu, Oguzhan Gunduz, Cem Bulent Ustundag   +11 more
wiley   +1 more source

A Bibliometric Analysis of Exosomes Associated with Rheumatic Diseases in the 21st Century. [PDF]

J Multidiscip Healthc
Zou Y, Wang S, Ao X, Zhang J, Chen E, Wang J, Luo J, Tao Q.   +7 more
europepmc   +1 more source

From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting

Macromolecular Materials and Engineering, EarlyView.
This review explores recent advances in 3D bioprinting, emphasizing printing technologies, bioink design, and emerging strategies such as cryogenic printing. Key challenges in biocompatibility, vascularization, and scalability are discussed, alongside opportunities for clinical translation.
Muhammad Wajid Ullah, Mazhar Ul‐Islam, Adeeb Shehzad, Sehrish Manan, Salman Ul Islam, Atiya Fatima, Abdullah Khamis Al‐Saidi, Mustapha El Hariri El Nokab, Juan Quevedo Sanchez, Khaled O. Sebakhy   +9 more
wiley   +1 more source

Mechanistic Insights Into Overloading-Induced Terminal Differentiation of TMJ Condylar Cartilage at the Single Cell Level. [PDF]

Smart Med
Zhou D, Jiang Y, Li Y, Zeng H, Li X, He Y, Wang X, Liang Y, Parizek V, Liu O, Tang Z, Zhou Y.   +11 more
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source