Results 271 to 280 of about 118,065 (344)

Perillyl alcohol promotes autophagy by suppressing the PI3K-AKT-mTOR signalling pathway in osteoarthritic chondrocytes in vitro. [PDF]

Sci Rep
Zhao D, Nong J, Li X, Tan J, Liao R, Chen Q, Qiu M.   +6 more
europepmc   +1 more source

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua, Guo‐Liang Wang, Wen‐Hao Duan, Xiao‐Heng Tang   +3 more
wiley   +1 more source

PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and alleviates chondrocyte osteoarthritis mediated by exosomal ANXA1. [PDF]

J Orthop Translat
Jia S, Yang Y, Liu J, Wang Z, Bai L.
europepmc   +1 more source

Monotropein Induced Ferroptosis to Alleviate the Progression of Hepatocellular Carcinoma via Regulating Nrf2/HO‐1/GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) exhibits a high global morbidity rate and ranks as the fourth leading cause of cancer‐related mortality worldwide. In response to the urgent need for effective HCC treatments, naturally occurring, botanical‐driven compounds have gained increasing attention.
Bing Shi, Yan‐Ping Li, Zhuo Gan, Pan Chen   +3 more
wiley   +1 more source

Landscape of Histone Posttranslational Modifications in Osteoarthritis. [PDF]

J Inflamm Res
Zhao S, Zheng J, Yue S, Chen X, Dong Y.
europepmc   +1 more source

Thin flap sulcus‐deepening trochleoplasty in patellar instability yields good functional outcomes without progressive cartilage deterioration in the short‐term follow‐up—A retrospective single‐surgeon cohort study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Thin‐flap sulcus‐deepening trochleoplasty with medial patellofemoral ligament reconstruction is a safe and effective procedure in patellar instability and high‐grade trochlear dysplasia, with no cartilage deterioration after 34.8 ± 20.9 months. Abstract Purpose Sulcus‐deepening trochleoplasty (TP) effectively treats patellofemoral (PF) instability (PFI)
Jannik Frings, Eva Janssen, Matthias Krause, Karl‐Heinz Frosch, Eik Vettorazzi, Andreas Weiler, Arno Schmeling   +6 more
wiley   +1 more source

Osteoarthritis as an evolutionary legacy: Biological ageing and chondrocyte hypertrophy. [PDF]

Osteoarthr Cartil Open
van der Kraan PM.
europepmc   +1 more source

Post‐operative joint stiffness after Bereiter trochleoplasty does not affect 2‐year improvement in patient‐reported outcomes. A prospective cohort study of 374 Bereiter trochleoplasties

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Bereiter trochleoplasty (TP) is a well‐described procedure to address trochlear dysplasia (TD). Post‐operative joint stiffness with reduced range of motion (ROM) is a common complication usually requiring arthroscopically assisted manipulation (AAM) with the removal of adhesions and scar tissue. Inferior clinical outcomes after TP have
Christian Dippmann, Christos Soleas, Anke Simone Rechter, Volkert Siersma, Kristoffer Weisskirchner Barfod, Peter Lavard   +5 more
wiley   +1 more source

Magnetic Nanoparticles Combined With Pulsed Electromagnetic Field Alleviate Chondrocyte Necroptosis in Osteoarthritis. [PDF]

FASEB J
Li X, Li J, Ji Z, Li C, Wu T, Song H, Yang X.   +6 more
europepmc   +1 more source

The patient acceptable symptomatic state for commonly used outcome scores 10 years after matrix‐associated autologous chondrocyte implantation

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To determine the Patient Acceptable Symptomatic State (PASS) thresholds for the Knee Injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee (IKDC), Lysholm and EuroQol 5 Dimensions (EQ‐5D) scores and to identify predictors of PASS at 10 years after matrix‐associated autologous chondrocyte ...
Kevin‐Arno Koch, Raphael Trefzer, Mustafa Hariri, Paul Mick, Tilman Walker, Stefanos Tsitlakidis, Johannes Weishorn   +6 more
wiley   +1 more source