Results 251 to 260 of about 118,322 (313)
Some of the next articles are maybe not open access.
Annals of the Rheumatic Diseases, 2022
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression.
Haiyan Zhang +13 more
semanticscholar +1 more source
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression.
Haiyan Zhang +13 more
semanticscholar +1 more source
The International Journal of Biochemistry & Cell Biology, 2003
The chondrocyte is the resident cell of cartilage that is a prominent tissue in the embryo acting as a template for the development of skeletal elements. In the adult, the distribution of permanent cartilage is much more restricted and is necessary for mechanical support, growth and movement.
Archer, C W, Francis-West, P
openaire +3 more sources
The chondrocyte is the resident cell of cartilage that is a prominent tissue in the embryo acting as a template for the development of skeletal elements. In the adult, the distribution of permanent cartilage is much more restricted and is necessary for mechanical support, growth and movement.
Archer, C W, Francis-West, P
openaire +3 more sources
ACS Applied Materials and Interfaces, 2020
Targeted delivery to the diseased cell or tissue is the key to the successful clinical use of nucleic acid drugs. In particular, delivery of microRNA-140 (miRNA-140, miR-140) into chondrocytes across the dense, nonvascular extracellular matrix of ...
Yujie Liang +7 more
semanticscholar +1 more source
Targeted delivery to the diseased cell or tissue is the key to the successful clinical use of nucleic acid drugs. In particular, delivery of microRNA-140 (miRNA-140, miR-140) into chondrocytes across the dense, nonvascular extracellular matrix of ...
Yujie Liang +7 more
semanticscholar +1 more source
Arthroscopy, 1996
Abstract The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non‐weight‐bearing areas of the affected joint to ...
D W, Jackson, T M, Simon
openaire +2 more sources
Abstract The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non‐weight‐bearing areas of the affected joint to ...
D W, Jackson, T M, Simon
openaire +2 more sources
Molecular characterisation of chondrocytes in autologous chondrocyte implantation
International Journal of Molecular Medicine, 2004Autologous chondrocyte implantation (ACI) relies on the use of cultured cells. However, the biosynthetic profile of cultured chondrocytes is shown to be altered during in vitro expansion. The purpose of this study therefore, was to examine the cellular phenotype of chondrocytes cultured for ACI and to determine the apoptotic index of cells implanted ...
M H, Zheng +6 more
openaire +2 more sources
Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes
Biochemical and Biophysical Research Communications, 2018Chondrocytes express many kinds of hormone receptors. The function of Follicle stimulating hormone (FSH) in the ovary is mediated by FSH receptor (FSHR). FSH receptor (FSHR) is found in many non-ovarian tissues, however it has been unclear if chondrocytes express FSHR.
Dehuan, Kong +9 more
openaire +2 more sources
Chondrocyte dedifferentiation and osteoarthritis (OA).
Biochemical Pharmacology, 2019Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage degradation but also synovial membrane inflammation, osteophyte formation and subchondral bone sclerosis. Medical care is mainly based on alleviating pain symptoms,
E. Charlier +7 more
semanticscholar +1 more source
Autologous Chondrocyte Implantation
The Journal of Bone & Joint Surgery, 2006Injuries to joint surfaces can result from acute high-impact or repetitive shear and torsional loads to the superficial zone of the articular cartilage architecture. The use of autologous chondrocyte implantation is promising and is associated with several potential long-term benefits.
Jones, D. G., Peterson, L.
openaire +5 more sources
1995
Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
openaire +2 more sources
Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
openaire +2 more sources
Science Translational Medicine, 2018
An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
openaire +2 more sources
An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
openaire +2 more sources