Results 281 to 290 of about 131,500 (355)

Loss of the miR-221/222 Cluster Promotes the Pathogenesis of Osteoarthritis in Inflamed Mouse Chondrocytes and Osteoarthritis Models. [PDF]

Inflammation
Liu X, Feng F, Jin Y, Ma C, Zhu Q, You Y, Gao M, Li X, Niu X, Wang J.   +9 more
europepmc   +1 more source

Piezo‐type mechanosensitive cation channel 1 in bone biomechanics and its multidimensional distribution characteristics in skeletal tissue

VIEW, EarlyView.
PIEZO1 is highly correlated with mechanical stimulation, controlling bone growth and remodeling, while showing specific distribution characteristics under distinct loads. Upon dialectical review, this manuscript proposes that PIEZO1 could serve as a target for osteoporosis and a quantitative indicator for monitoring bone health in real‐time.
Chunyu Zhang, Yuehong Wang
wiley   +1 more source

A New Way to Engineer Cell Sheets for Articular Cartilage Regeneration. [PDF]

J Funct Biomater
Tan TL, Tseng Y, Li JW, Yang CT, Chen HY, Lee HI, Liu JJ, Yang YY, Tseng H.   +8 more
europepmc   +1 more source

Internal diseases and molecular mechanisms causing slipped capital femoral epiphysis in children. [PDF]

World J Orthop
Chen YF, Ning K, Xie YY, Liu C, Ding YT, Tang ZW, Wen J, Xiao S, Li YF.   +8 more
europepmc   +1 more source

The MEK-ERK1/2 signaling pathway regulates hyaline cartilage formation and the redifferentiation of dedifferentiated chondrocytes in vitro.

, 2018
Xuezong Wang, Yan Xue, Weiwei Ye, Jian Pang, Liu Zhen-fen, Yuelong Cao, Yuxin Zheng, Dao-Fang Ding   +7 more
openalex   +1 more source

Recent Advances in Therapeutic Approaches for Knee Osteoarthritis: a Narrative Review. [PDF]

Biomol Ther (Seoul)
Hossain MS, Lee HJ, Hossain R, Kim CM, Lee CJ, Hwang SC.   +5 more
europepmc   +1 more source

Butin inhibits osteoarthritis progression by modulating the Nrf2/HO-1 signaling pathway and inhibiting NF-κB signaling. [PDF]

Sci Rep
Zhou P, Chang J, Wei X, Zhu C, Yang J, Wang C, Hu Y, Zhang C.   +7 more
europepmc   +1 more source

MSC-EVs alleviate osteoarthritic joint pain and degeneration by suppressing IL-1β/NGF signaling. [PDF]

Genes Dis
Teo KYW, Wen C, Wong RCW, Toh WS.
europepmc   +1 more source

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model. [PDF]

Front Bioeng Biotechnol
Huang Z, Zhao W, Lan J, Lin Y, Gao X.
europepmc   +1 more source

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression

International Journal of Molecular Sciences, 2020
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily caused by trauma induced by an external force or by age-related cartilage damage.
Yeri Alice Rim, Yoojun Nam, Ji Hyeon Ju
exaly   +2 more sources