Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-β-mediated chondrocyte proliferation and proteoglycan synthesis [PDF]
, 2003 Alwin Scharstuhl +6 more
openalex +1 more source
IGF-I signalling in bone growth:inhibitory actions of dexamethasone and IL-1beta [PDF]
, 2007 Ahmed, S.F. +4 more
core +1 more source
Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]
, 2016 Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core
Advances in Medical Devices for Augmented Acupuncture Therapy
Advanced Science, EarlyView.Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai +7 more
wiley +1 more source
Stem Cell Research & TherapyBackground Osteoarthritis (OA) is one of the most prevalent degenerative joint diseases, while the mechanism by which extracellular vesicles (EVs) promote chondrocyte regeneration remains unclear. The study assessed the effect of hypoxic mesenchymal stem
Haifeng Zhang +10 more
doaj +1 more source
Secondary chondrocyte-derived Ihh stimulates proliferation of periosteal cells during chick development [PDF]
, 2003 Paul Buxton +3 more
openalex +1 more source
Advanced Science, EarlyView.Microparticle‐based antioxidants capable of scavenging multiple reactive oxygen species (ROS) have been developed. When retained within the articular cavity of osteoarthritic mice, Mn‐ or Co‐AKT‐MPs protect the inherent homeostasis between cartilage anabolism and catabolism, and inhibit synovial inflammation.
Ronghui Deng +11 more
wiley +1 more source
MiR-379-5p Promotes Chondrocyte Proliferation via Inhibition of PI3K/Akt Pathway by Targeting YBX1 in Osteoarthritis. [PDF]
Cartilage, 2022 Zhang H, Zheng W, Li D, Zheng J.
europepmc +1 more source
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes [PDF]
, 2004 Hirotaka Chikuda +13 more
openalex +1 more source
Advanced Science, EarlyView.This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang +10 more
wiley +1 more source