Results 141 to 150 of about 38,162 (257)

RFLNA mitigates heat stress-impaired chondrocyte proliferation and vertebral development through cytoskeletal regulation in pigs. [PDF]

J Anim Sci Biotechnol
Yang X, Xie Y, Luo Y, Wang Y, Yang L, Zhang L, Xue P, Zha C, Fang M.   +8 more
europepmc   +1 more source

Mechanism of Abnormal Chondrocyte Proliferation Induced by Piezo1-siRNA Exposed to Mechanical Stretch. [PDF]

Biomed Res Int, 2020
Sun Y, Leng P, Li D, Gao H, Li Z, Li C, Zhang H.   +6 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature. [PDF]

Int J Mol Med
Liu X, Yan C, Deng X, Jia J.
europepmc   +1 more source

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway

Phytotherapy Research, EarlyView.
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che, Qing Feng, Zhixia Zhao, Jingying Sun, Weihao Ren, Yangmeng Feng, Cuixiang Xu, Xu‐Hui Li   +7 more
wiley   +1 more source

BMP8A, TGF-β1 regulates chicken chondrocyte proliferation, differentiation, and apoptosis induced by Thiram. [PDF]

Anim Biosci
Lu Y, Xu H, Ji X, Zhou Y, Hu Z, Amevor FK, Du R, Zhao X, Liu Y, Wang Y.   +9 more
europepmc   +1 more source

Effects of Leptin on Differentiation and Proliferation of Chondrocytes

Journal of Hard Tissue Biology, 2019
Zhang, Shai, Zhao, Yang, Wang, Yifan, Muhammad, Ishfaq, Ma, Ning, Bie, Lianyu, Zhao, Lidong, Zhu, Zihan, Meng, Xinghua, Cong, Linlin, Hu, Lan, Xiao, Jianhua   +11 more
openaire   +2 more sources

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model. [PDF]

Front Bioeng Biotechnol
Huang Z, Zhao W, Lan J, Lin Y, Gao X.
europepmc   +1 more source

NFI-C Is Required for Epiphyseal Chondrocyte Proliferation during Postnatal Cartilage Development. [PDF]

Mol Cells, 2020
Lee DS, Roh SY, Choi H, Park JC.
europepmc   +1 more source