Results 151 to 160 of about 38,162 (257)

Low-Intensity Pulsed Ultrasound Alleviates Osteoarthritis Condition Through Focal Adhesion Kinase-Mediated Chondrocyte Proliferation and Differentiation. [PDF]

Cartilage, 2021
Sang F, Xu J, Chen Z, Liu Q, Jiang W.
europepmc   +1 more source

Exploiting Device Deformability for Fluid and Particle Manipulation

Small, EarlyView.
Deformable devices enable fluid and particle manipulation modes that are inaccessible to rigid platforms. This review examines soft materials and architectures that translate controlled deformation into microscale fluid operations such as pumping, valving, mixing, and particle handling.
Zhiyang Hong, Xiaoyue Kang, Dan Yuan, Nam‐Trung Nguyen, Jun Zhang   +4 more
wiley   +1 more source

Reg3β promotes chondrocyte proliferation and ECM metabolism during acetabular roof remodeling in a rat model of DDH‑induced residual dysplasia. [PDF]

Mol Med Rep
Wang P, Li M, Wang W, Sun W, Zhen W, Sun Q, Ning B, Su G, Wang X.   +8 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Hepatocyte Growth Factor-Mediated Chondrocyte Proliferation Induced by Adipose-Derived MSCs from Osteoarthritis Patients and Its Synergistic Enhancement by Hyaluronic Acid. [PDF]

Int J Mol Sci
Won SJ, Lee HJ, Kim DY, Noh H, Lee SY, Yoo JA, Jeon YS, Shin H, Ryu DJ.   +8 more
europepmc   +1 more source

BMSC-derived exosomes from congenital polydactyly tissue alleviate osteoarthritis by promoting chondrocyte proliferation. [PDF]

Cell Death Discov, 2020
Zhou X, Liang H, Hu X, An J, Ding S, Yu S, Liu C, Li F, Xu Y.   +8 more
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression. [PDF]

J Cell Commun Signal
Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY.   +5 more
europepmc   +1 more source

Altered IHH signaling contributes to reduced chondrocyte proliferation in the growth plate of MPS VII mice. [PDF]

Mol Genet Metab Rep, 2020
Jiang Z, Derrick-Roberts ALK, Byers S.
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source