Considerations and challenges of septic arthritis and osteomyelitis
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
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Osteochondrosis in horses: An overview of genetic and other factors
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez+2 more
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The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25
Metastatic progression is characterised by extensive remodelling of the extracellular matrix, primarily mediated by secreted proteases, including ADAMTS family members. Rainero and colleagues found that the small GTPase Rab25 promoted the expression of ADAMTS5 in ovarian cancer cells through the activation of the NF‐κB signalling pathway.
Shengnan Yuan+7 more
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Fibroblast Growth Factor 19 Disrupts Cartilage Development Via the FGFR4/β-catenin Axis. [PDF]
Chen H+6 more
europepmc +1 more source
Research progress on exosomes from different sources in osteoarthritis and cartilage injury. [PDF]
Yang Z+6 more
europepmc +1 more source
Pig meniscus single-cell sequencing reveals highly active red zone chondrocyte populations involved in stemness maintenance and vascularization development. [PDF]
Mankowska M+8 more
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APOPTOSIS AND PROLIFERATION OF GROWTH PLATE CHONDROCYTES IN RABBITS [PDF]
The growth plates of the femoral head of Japanese white rabbits aged 5, 10, 15 and 20 weeks were stained for apoptotic and proliferating chondrocytes using the TUNEL and PCNA antibody staining techniques. Both TUNEL- and PCNA-positive chondrocytes were detected in all of the specimens.
Toshimi Aizawa+2 more
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Interleukin 1: a regulator of chondrocyte proliferation
Immunology Letters, 1989Human interleukin 1 beta (IL-1 beta), at low concentrations (0.3-1 ng/ml), decreased by 95% the efficiency of colony formation in soft agar by rabbit articular chondrocytes. Furthermore, interleukin 1 (IL-1) suppressed by 50-60% the incorporation of [3H]thymidine into DNA in high density chondrocyte cultures on plastic dishes in the presence of 10 ...
Yukio Kato+4 more
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The proliferation of chondrocytes and pannus in adjuvant arthritis
Virchows Archiv B Cell Pathology, 1977Cell proliferation in the pannus formation of adjuvant arthritis was studied by autoradiography. It was found that after day 9 an increased cell proliferation starts in the joint capsule recessus and synovial villi on the injected side. From these proliferating cells a pannus, which during the first phase frequently consists only of few cell layers ...
A. Wild, W. Mohr
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