Results 271 to 280 of about 57,848 (292)

In Vitro Cartilage Regeneration From Proliferated Adult Elastic Chondrocytes

Annals of Plastic Surgery, 2005
The purpose of this study was to investigate cellular feasibility in the proliferation and differentiation status of adult chondrocytes for cartilage regeneration in comparison to fetal chondrocytes. Primary cells were isolated from adult (n = 6) and fetal (n = 6) sheep ear cartilages and expanded in 10% fetal bovine serum (FBS) containing Ham's F12 ...
Shinichi, Terada, Julie R, Fuchs, Hiroshi, Yoshimoto, Dario O, Fauza, Joseph P, Vacanti   +4 more
openaire   +2 more sources

Modulation of chondrocyte proliferation by ascorbic acid and BMP‐2

Journal of Cellular Physiology, 1998
Chondrocytes show an unusual ability to thrive under serum-free conditions as long as insulin, thyroxine, and cysteine are present. Studies with sternal chondrocytes from chick embryos indicate that thymidine incorporation in chondrocytes cultured under serum-free conditions is 30-50% of that seen with fetal bovine serum (FBS).
R, Venezian, B J, Shenker, S, Datar, P S, Leboy   +3 more
openaire   +2 more sources

Human chondrocyte proliferation and matrix synthesis cultured in Atelocollagen® gel

Journal of Biomedical Materials Research, 2000
To evaluate the potential of Atelocollagen gel as a carrier for chondrocyte transplantation, histological and biochemical characteristics of the chondrocytes in gel culture were compared with those in conventional monolayer cultures. Articular chondrocytes from 20 patients were isolated by enzyme digestion, embedded in Atelocollagen gel, and cultured ...
Y, Uchio, M, Ochi, M, Matsusaki, H, Kurioka, K, Katsube   +4 more
openaire   +2 more sources

Topography-Guided Proliferation: Distinct Surface Microtopography Increases Proliferation of ChondrocytesIn Vitro

Tissue Engineering Part A, 2015
Chondrocyte-based cartilage repair techniques require control of articular chondrocyte expansion ex vivo. Articular chondrocytes have limited availability, and prolonged culturing to obtain a cell number sufficient for clinical use often results in phenotypic alterations and increased costs.
Joergensen, Natasja Leth, Le, Dang Quang Svend, Andersen, Ole Zoffmann, Foss, Morten, Danielsen, Carl Christian, Foldager, Casper Bindzus, Lind, Martin, Lysdahl, Helle   +7 more
openaire   +2 more sources

Defective chondrocyte proliferation and differentiation in osteochondromas of MHE patients

Bone, 2006
Multiple hereditary exostoses (MHE) is an autosomal dominant skeletal disorder caused by mutations in one of the two EXT genes and characterized by multiple osteochondromas that generally arise near the ends of growing long bones. Defective endochondral ossification is likely to be involved in the formation of osteochondromas.
Catherine, Benoist-Lasselin, Emmanuel, de Margerie, Linda, Gibbs, Sarah, Cormier, Caroline, Silve, Gisèle, Nicolas, Martine, LeMerrer, Jean-Francois, Mallet, Arnold, Munnich, Jacky, Bonaventure, Louise, Zylberberg, Laurence, Legeai-Mallet   +11 more
openaire   +2 more sources

Transcriptional networks controlling chondrocyte proliferation and differentiation during endochondral ossification

Pediatric Nephrology, 2009
During endochondral ossification bones are formed as cartilage templates in which chondrocytes proliferate, differentiate into hypertrophic chondrocytes and are gradually replaced by bone. Postnatally, remnants of embryonic chondrocytes remain in a restricted domain between the ossified regions of the bones forming the growth plate.
Wülling, Manuela, Vortkamp, Andrea
openaire   +2 more sources

Regulation of Tcf7 by Runx2 in chondrocyte maturation and proliferation

Journal of Bone and Mineral Metabolism, 2010
Runx2 plays important roles in the regulation of chondrocyte differentiation and proliferation; however, the Runx2 target molecules still remain to be investigated. We searched the genes upregulated by the introduction of Runx2 into Runx2(-/-) chondrocytes using microarray and found that Tcf7 is upregulated by Runx2.
Masaki, Mikasa, Satoshi, Rokutanda, Hisato, Komori, Kosei, Ito, Ying Sze, Tsang, Yuki, Date, Carolina A, Yoshida, Toshihisa, Komori   +7 more
openaire   +2 more sources

Fabrication of chondroitin sulfate calcium complex and its chondrocyte proliferation in vitro

Carbohydrate Polymers, 2021
Aurore Richel
exaly  

Proliferation and differentiation of chondrocytes in cell culture.

Physiologia Bohemoslovaca, 1983
Chondrocytes freshly explanted from the sternal cartilage of 14- to 16-day-old chick embryos proliferate and differentiate in cell culture in a serum-free medium as well as in a medium containing 10% foetal calf serum. A comparable degree of multiplication and differentiation was found in chondrocytes cultivated in the serum-free medium containing ...
M, Baudysová, J, Michl
openaire   +1 more source

Salidroside enhances proliferation and maintains phenotype of articular chondrocytes for autologous chondrocyte implantation (ACI) via TGF-β/Smad3 Signal

Biomedicine and Pharmacotherapy, 2020
Li Zheng, Jinmin Zhao, Miao Sun
exaly