Results 251 to 260 of about 57,848 (292)

Effects of Pulsed Electromagnetic Fields on Human Articular Chondrocyte Proliferation

Connective Tissue Research, 2001
Low-energy, low-frequency pulsed electromagnetic fields (PEMFs) can induce cell proliferation in several cell culture models. In this work we analysed the proliferative response of human articular chondrocytes, cultured in medium containing 10% FBS, following prolonged exposure to PEMFs (75 Hz, 2.3 mT), currently used in the treatment of some ...
DE MATTEI, Monica, CARUSO, Angelo, PEZZETTI, Furio, PELLATI, Agnese, STABELLINI, Giordano, SOLLAZZO, Vincenzo, TRAINA, Gian Carlo   +6 more
openaire   +4 more sources

Chondrocyte Proliferation and Differentiation

2011
The skeletal elements of the axial and appendicular skeleton are preformed as cartilage templates by a mechanism called endochondral ossification. During this process, a cartilage template is formed in which chondrocytes proliferate and differentiate into hypertrophic chondrocytes and are gradually replaced by bone.
Manuela, Wuelling, Andrea, Vortkamp
openaire   +4 more sources

Mechanical compression modulates proliferation of transplanted chondrocytes

Journal of Orthopaedic Research, 2000
AbstractThe presence of an appropriate number of reparative cells in an articular cartilage defect is probably necessary for consistent and successful repair. Following the transplantation of chondrocytes into a defect, cell proliferation may modulate local defect cellularity.
K W, Li, Y H, Falcovitz, J P, Nagrampa, A C, Chen, L M, Lottman, J Y, Shyy, R L, Sah   +6 more
openaire   +2 more sources

Interleukin 1: a regulator of chondrocyte proliferation

Immunology Letters, 1989
Human interleukin 1 beta (IL-1 beta), at low concentrations (0.3-1 ng/ml), decreased by 95% the efficiency of colony formation in soft agar by rabbit articular chondrocytes. Furthermore, interleukin 1 (IL-1) suppressed by 50-60% the incorporation of [3H]thymidine into DNA in high density chondrocyte cultures on plastic dishes in the presence of 10 ...
M, Iwamoto, T, Koike, K, Nakashima, K, Sato, Y, Kato   +4 more
openaire   +2 more sources

FBLN1 promotes chondrocyte proliferation by increasing phosphorylation of Smad2

Journal of Orthopaedic Science, 2022
The role of fibulin-1 or FBLN1 in chondrocyte proliferation has not been reported so far. In this study, we aimed to verify whether FBLN1 promotes chondrocyte proliferation in elderly patients with knee osteoarthritis by phosphorylating Smad2.Chondrocytes were isolated from cartilage samples collected from elderly patients with osteoarthritis (n = 6 ...
Gang, Xu, Xiang, Geng, Fan, Yang, Haijiao, Zhang   +3 more
openaire   +2 more sources

Platelet Supernatant Promotes Proliferation of Auricular Chondrocytes and Formation of Chondrocyte Mass

Annals of Plastic Surgery, 2000
Recently proposed procedures for in vitro generation of new cartilage may be difficult to perform in humans because so many chondrocytes are needed for tissue engineering. In this study the authors investigated new, efficient, low-cost techniques for the isolation and culture of chondrocytes from the ear cartilage of the rabbit.
S Y, Yang, S T, Ahn, J W, Rhie, K Y, Lee, J H, Choi, B J, Lee, G T, Oh   +6 more
openaire   +2 more sources

Autologous chondrocyte implantation: cells phenotype and proliferation analysis

Knee Surgery, Sports Traumatology, Arthroscopy, 2001
AbstractThe phenotype and proliferation of human chondrocytes in culture were analyzed before they were implanted as autologous graft in cartilage lesions. During ten autologous chondrocyte implantations in articular cartilage lesions of the knee in ten patients, small amounts of cells to be implanted were collected and analyzed by morphology ...
A, Gigante, C, Bevilacqua, C, Zara, M, Travasi, C, Chillemi   +4 more
openaire   +2 more sources

Cell cycle genes in chondrocyte proliferation and differentiation

Matrix Biology, 1999
Coordinated proliferation and differentiation of growth plate chondrocytes controls longitudinal growth of endochondral bones. While many extracellular factors regulating these processes have been identified, much less is known about the intracellular mechanisms transducing and integrating these extracellular signals. Recent evidence suggests that cell
F, Beier, T A, Leask, S, Haque, C, Chow, A C, Taylor, R J, Lee, R G, Pestell, R T, Ballock, P, LuValle   +8 more
openaire   +2 more sources

Runx3 regulates chondrocyte phenotype by controlling multiple genes involved in chondrocyte proliferation and differentiation

Molecular Biology Reports, 2020
Chondrocytes are the sole cell type present within cartilage, and play pivotal roles in controlling the formation and composition of health cartilage. Chondrocytes maintain cartilage homeostasis through proliferating, differentiating and synthesizing different types of extracellular matrices.
Zhenwei Zhou, Baojin Yao, Daqing Zhao
openaire   +2 more sources