Results 231 to 240 of about 731,089 (287)
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel +10 more
wiley +1 more source
Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
wiley +1 more source
ABSTRACT Mathematical models describing physical or biological processes are often involved and need a lot of parameters whose values may be unknown and hence must be estimated. Some parameters may have a strong impact on the solution and are hence important to know in order to obtain accurate results, whereas other parameters may have little impact on
Henry Jäger, Bernd Simeon
wiley +1 more source
ABSTRACT Objective This study aimed to evaluate whether the combination of photobiomodulation and platelet‐rich plasma therapy provides superior anti‐inflammatory and joint‐protective effects compared to individual treatments in an experimental model of osteoarthritis.
Anne Missrie +5 more
wiley +1 more source
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
wiley +1 more source
Abstract A 5‐month‐old female domestic shorthair cat was presented due to a 3‐month history of intermittent hindlimb lameness. Physical examination, radiographs and computed tomography were indicative of osteochondritis dissecans (OCD) in the right medial femoral condyle, accompanied by bilateral medial patellar luxation (MPL) and bilateral hip ...
Ute Wiesbauer +3 more
wiley +1 more source
ABSTRACT Objective This study aimed to evaluate the impact of pathogenic genetic variants on growth outcomes following 3 years of recombinant human growth hormone (rhGH) therapy in children born small for gestational age with persistent short stature (SGA‐SS). Design A retrospective cohort study.
Sanghee Park +15 more
wiley +1 more source
PIEZO1 supports adaptive matrix remodeling during tendon homeostasis but has a distinct role following injury. ScxCre‐driven Piezo1 depletion reduced Scx+ cell recruitment/accumulation within the healing defect of the patellar tendon and was associated with accelerated collagen remodeling and improved mechanical recovery.
Nicole A. Chittim +4 more
wiley +1 more source
What's Your Diagnosis? Large Mediastinal Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz +7 more
wiley +1 more source
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source

