Results 221 to 230 of about 38,162 (257)

Platelet Supernatant Promotes Proliferation of Auricular Chondrocytes and Formation of Chondrocyte Mass

Annals of Plastic Surgery, 2000
Recently proposed procedures for in vitro generation of new cartilage may be difficult to perform in humans because so many chondrocytes are needed for tissue engineering. In this study the authors investigated new, efficient, low-cost techniques for the isolation and culture of chondrocytes from the ear cartilage of the rabbit.
S Y, Yang, S T, Ahn, J W, Rhie, K Y, Lee, J H, Choi, B J, Lee, G T, Oh   +6 more
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FBLN1 promotes chondrocyte proliferation by increasing phosphorylation of Smad2

Journal of Orthopaedic Science, 2022
The role of fibulin-1 or FBLN1 in chondrocyte proliferation has not been reported so far. In this study, we aimed to verify whether FBLN1 promotes chondrocyte proliferation in elderly patients with knee osteoarthritis by phosphorylating Smad2.Chondrocytes were isolated from cartilage samples collected from elderly patients with osteoarthritis (n = 6 ...
Gang, Xu, Xiang, Geng, Fan, Yang, Haijiao, Zhang   +3 more
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APOPTOSIS AND PROLIFERATION OF GROWTH PLATE CHONDROCYTES IN RABBITS

The Journal of Bone and Joint Surgery. British volume, 1997
The growth plates of the femoral head of Japanese white rabbits aged 5, 10, 15 and 20 weeks were stained for apoptotic and proliferating chondrocytes using the TUNEL and PCNA antibody staining techniques. Both TUNEL- and PCNA-positive chondrocytes were detected in all of the specimens.
T, Aizawa, S, Kokubun, Y, Tanaka
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Influence of ion channels on the proliferation of human chondrocytes

Biorheology: The Official Journal of the International Society of Biorheology, 2002
The goal of the study was to examine connections between ion channel activity and the proliferation of human chondrocytes. Chondrocytes were isolated form human osteoarthritic knee joint cartilage. In this study the concentration‐dependent influence of the ion channel modulators tetraethylammonium (TEA), 4‐aminopyridine (4‐AP), 4
David, Wohlrab, Susanne, Lebek, Thomas, Krüger, Heiko, Reichel   +3 more
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Mechanical compression modulates proliferation of transplanted chondrocytes

Journal of Orthopaedic Research, 2000
AbstractThe presence of an appropriate number of reparative cells in an articular cartilage defect is probably necessary for consistent and successful repair. Following the transplantation of chondrocytes into a defect, cell proliferation may modulate local defect cellularity.
K W, Li, Y H, Falcovitz, J P, Nagrampa, A C, Chen, L M, Lottman, J Y, Shyy, R L, Sah   +6 more
openaire   +2 more sources

Suppression of growth plate chondrocyte proliferation by corticosteroids

Pediatric Nephrology, 2000
Growth depression is a side effect of high-dose glucocorticoid therapy in childhood. It is partially mediated by alterations of the somatotropic hormone axis and partially by direct local effects on growth plate chondrocytes. The mechanisms of interaction of corticosteroids and somatotropic and calciotropic hormones at the cellular level were recently ...
G, Klaus, C, Jux, P, Fernandez, J, Rodriguez, R, Himmele, O, Mehls   +5 more
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Regulation of Tcf7 by Runx2 in chondrocyte maturation and proliferation

Journal of Bone and Mineral Metabolism, 2010
Runx2 plays important roles in the regulation of chondrocyte differentiation and proliferation; however, the Runx2 target molecules still remain to be investigated. We searched the genes upregulated by the introduction of Runx2 into Runx2(-/-) chondrocytes using microarray and found that Tcf7 is upregulated by Runx2.
Masaki, Mikasa, Satoshi, Rokutanda, Hisato, Komori, Kosei, Ito, Ying Sze, Tsang, Yuki, Date, Carolina A, Yoshida, Toshihisa, Komori   +7 more
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Cell cycle genes in chondrocyte proliferation and differentiation

Matrix Biology, 1999
Coordinated proliferation and differentiation of growth plate chondrocytes controls longitudinal growth of endochondral bones. While many extracellular factors regulating these processes have been identified, much less is known about the intracellular mechanisms transducing and integrating these extracellular signals. Recent evidence suggests that cell
F, Beier, T A, Leask, S, Haque, C, Chow, A C, Taylor, R J, Lee, R G, Pestell, R T, Ballock, P, LuValle   +8 more
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Inhibition effect of osthole on proliferation of rat chondrocytes

Journal of Chinese Integrative Medicine, 2012
To investigate the effects of osthole on chondrocyte proliferation in vitro.Primary rat chondrocytes were isolated from the femoral head of newborn rats using collagenase digestion and cultured in Dulbecco's modified Eagle's medium. The proliferation of primary chondrocytes was assessed in second-passage cultures using cell counting kit-8 and the ...
Dao-fang, Ding, Song-pu, Wei, Xiao-feng, Li, Xiao-gang, Zhang, Hong-sheng, Zhan, Tie-li, Duan, Yue-long, Cao   +6 more
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Runx3 regulates chondrocyte phenotype by controlling multiple genes involved in chondrocyte proliferation and differentiation

Molecular Biology Reports, 2020
Chondrocytes are the sole cell type present within cartilage, and play pivotal roles in controlling the formation and composition of health cartilage. Chondrocytes maintain cartilage homeostasis through proliferating, differentiating and synthesizing different types of extracellular matrices.
Zhenwei Zhou, Baojin Yao, Daqing Zhao
exaly   +3 more sources