Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Advanced Materials, EarlyView.Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis
Frontiers in Bioengineering and Biotechnology, 2018 Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary diseases thought to be major factors driving the process of articular cartilage ...
Swarna Raman +2 more
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EFFECT OF EXTRACELLULAR CHONDROITIN SULFATE ON CULTURED CHONDROCYTES [PDF]
, 1974 Dongyan Huang
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Advanced Materials, EarlyView.Understanding the bi‐directional crosstalk between cells and their surrounding extracellular matrix (ECM) is critical for tissue engineering. This study presents a chemoselective strategy for proteomic profiling of newly deposited ECM from resident cells.
Zihan Ling +9 more
wiley +1 more source
Effects of Immune Cells and Cytokines on Different Cells in OA
Journal of Inflammation Research, 2023 Pan Luo,* Qiling Yuan,* Xianjie Wan, Mingyi Yang, Peng Xu Department of Joint Surgery, HongHui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710054, People’s Republic of China*These authors contributed equally to this ...
Luo P, Yuan Q, Wan X, Yang M, Xu P
doaj
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
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Cartilage Tissue Engineering Via Icariin and Adipose-derived Stem Cells in Fibrin Scaffold
Advanced Biomedical Research, 2018 Background: Nowadays, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. This study evaluates the function of herbal extracts icariin (ICA), the major pharmacological constituent of herba Epimedium, compared with ...
Maryam Bahrami +4 more
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4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa +4 more
wiley +1 more source
Pig articular cartilage in organ culture. Effect of enzymatic depletion of the matrix on response of chondrocytes to complement-sufficient antiserum against pig erythrocytes. [PDF]
, 1974 S J Millroy, A. Robin Poole
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3D‐Printed Unibody Microfluidic Devices for Organ‐on‐Chip Applications
Advanced Materials Technologies, EarlyView.A practical approach is demonstrated to 3D printing unibody microfluidic Organ‐on‐Chip (OoC) devices using commercial resins and desktop DLP printers. The demonstrated functional devices support 2D monolayers, 3D spheroids, and barrier tissues. With optimised design and post‐processing techniques, leak‐free, biocompatible microchannels and membranes ...
Louis Jun Ye Ong +8 more
wiley +1 more source