Results 191 to 200 of about 213,570 (404)

On a mathematical model for tissue regeneration [PDF]

open access: yesarXiv
We propose a PDE-ODE model for tissue regeneration, obtained by parabolic upscaling from kinetic transport equations written for the mesoscopic densities of mesenchymal stem cells and chondrocytes which evolve in an artificial scaffold impregnated with hyaluron.
arxiv  

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou   +5 more
wiley   +1 more source

Biochemical similarity between cultured chondrocytes and in situ chondrocytes by chemometric analysis from FTIR microspectroscopy

open access: yesBiotechnology Reports, 2019
Background aims: Fourier Transform Infrared Micro-spectroscopy (FTIRM) is an emerging tool that obtains images with biochemical information of samples that are too small to be chemically analyzed by conventional Fourier transform infrared (FTIR ...
Monica Maribel Mata-Miranda   +5 more
doaj  

Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation

open access: yesAdvanced NanoBiomed Research, EarlyView.
The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington   +3 more
wiley   +1 more source

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

open access: yesNature, 2019
Steve Stegen   +18 more
semanticscholar   +1 more source

TBBPA exposure causes cartilage cell damage in both in vitro and in vivo models

open access: yesEcotoxicology and Environmental Safety
Tetrabromobisphenol A (TBBPA) is a widely used flame retardant. TBBPA is a persistent pollutant that is difficult to degrade and causes sustained pollution to the environment.
Bohao Yin   +3 more
doaj  

Decoding Cytokine Dynamics: Wharton’s Jelly Stromal Cells and Chondro-Differentiates in PHA-Stimulated Co-Culture

open access: yesCells
Introduction: Articular cartilage damage presents a significant clinical challenge, with limited options for effective regeneration. Mesenchymal stromal cells (MSCs) derived from Wharton’s jelly (WJ) are a promising cell source for cartilage repair due ...
Raja Sundari Meenakshi Sundaram   +10 more
doaj   +1 more source

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