Results 191 to 200 of about 216,956 (381)

Molten‐Salt‐Mediated Synthesis of Atomic Manganese/Cobalt Catalysts on Bioceramic Microparticles for Catalytic Anti‐Osteoarthritis Treatments

open access: yesAdvanced Science, EarlyView.
Microparticle‐based antioxidants capable of scavenging multiple reactive oxygen species (ROS) have been developed. When retained within the articular cavity of osteoarthritic mice, Mn‐ or Co‐AKT‐MPs protect the inherent homeostasis between cartilage anabolism and catabolism, and inhibit synovial inflammation.
Ronghui Deng   +11 more
wiley   +1 more source

Biosynthesis of proteoglycans by chick limb bud chondrocytes

open access: hybrid, 1978
S. De Luca   +2 more
openalex   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

Effect of Somatomedin-C/Insulin-Like Growth Factor I and Growth Hormone on Cultured Growth Plate and Articular Chondrocytes [PDF]

open access: bronze, 1989
Stephen B. Trippel   +5 more
openalex   +1 more source

A Study of Skeletal Stem Cell Dynamics and Its Potential Applications in the Design of a Titanium Implant for Senile Osteoporosis

open access: yesAdvanced Science, EarlyView.
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan   +12 more
wiley   +1 more source

Biological Effect of Estradiol on phosphatase activities in rabbit cultured chondrocytes [PDF]

open access: bronze, 1981
Antonio Carrascosa   +3 more
openalex   +1 more source

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

open access: yesAdvanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong   +12 more
wiley   +1 more source

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