Results 201 to 210 of about 222,465 (345)

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

Proceedings of the National Academy of Sciences of the United States of America, 2014
Liu Yang, K. Tsang, Hoi-ching Tang, D. Chan, K. Cheah   +4 more
semanticscholar   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes. [PDF]

Nat Commun
Yanagihara Y, Takahashi M, Izumi Y, Kinoshita T, Takao M, Bamba T, Imai Y.   +6 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

A Comprehensive Review of Auto- and Allogeneic Chondrocyte Transplantation in Animals and Humans From 1965 to 2025. [PDF]

Cartilage
Osiecka-Iwan A, Hyc A, Malejczyk J, Moskalewski S.   +3 more
europepmc   +1 more source

OMIC investigation of the chondrocyte response to varying mechanical load: assessment of impact stress [PDF]

, 2019
S.M. Higgins, R. Jones, K. Lawrence, S. Richardson, P. Townsend   +4 more
openalex   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Initiation of Chondrocyte Self-Assembly Requires an Intact Cytoskeletal Network

, 2016
Jennifer K. Lee, Jerry C. Hu, Soichiro Yamada, Kyriacos A. Athanasiou   +3 more
openalex   +1 more source

KLF2 reduces dexamethasone-induced injury to growth plate chondrocytes by inhibiting the Runx2-mediated PI3K/AKT and ERK signalling pathways

, 2022
Yulong Ma, Peng Tao, Xudong Yao, Chaonan Sun, Xiaowei Wang   +4 more
openalex   +1 more source