Results 241 to 250 of about 222,465 (345)

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism. [PDF]

Cell Death Discov
Liu K, Zhang X, Ning B, Liu R, Wang C, Cheng L, Zheng W, Wei J.   +7 more
europepmc   +1 more source

Sustained Results in Long-Term Follow-Up of Autologous Chondrocyte Implantation (ACI) for Distal Femur Juvenile Osteochondritis Dissecans (JOCD) [PDF]

, 2018
Jennifer J. Beck, Dai Sugimoto, Lyle J. Micheli   +2 more
openalex   +1 more source

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, EarlyView.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

Spermidine-encapsulated chondroitin sulfate methacryloyl hydrogel delivery system for remodeling bone homeostasis in rheumatoid arthritis. [PDF]

Mater Today Bio
Wang X, He J, Hong Y, Jie L, Wu B, Shen J, Zhou G, Wang Q.   +7 more
europepmc   +1 more source

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

Proceedings of the National Academy of Sciences of the United States of America, 2014
Christopher J O'Conor, H. Leddy, Halei C. Benefield, W. Liedtke, F. Guilak   +4 more
semanticscholar   +1 more source

Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation

iMetaOmics, EarlyView.
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu, Fan Xiao, Qinjun Zhang, Yao Xie, Mengmeng Wang, Jesus Simal‐Gandara, Yan Liu, Thomas Efferth, Weisu Huang, Jianfu Shen, Jianbo Xiao   +10 more
wiley   +1 more source

Effects of Surface Treatments on Innovative Additively Manufactured Scaffolds: Implications for Biocompatibility in Bone Tissue Engineering. [PDF]

Life (Basel)
Zhao Q, Fischer F, Voshage M, Jauer L, Kopp A, Praster M, Groven RVM, Schleifenbaum JH, Eschweiler J, Kobbe P, Buhl EM, Hildebrand F, Balmayor ER, Greven J.   +13 more
europepmc   +1 more source

Decellularized Membrane Derived from the Cell-Produced Extracellular Matrix of 1-Day-Old Porcine Cartilage Can Be a Substitute for Periosteal Patches in Autologous Chondrocyte Implantation

Minh‐Dung Truong, Thanh-Tam Nguyen-Thi, Thanh-Tan Nguyen-Ngoc, Bich-Tram Vo-Ngoc, Hoang-Yen Duong-Thi, Hoài Thương Nguyễn, Dong Van Hoang, Phuong Bui, Khanh Bui, Phuong Le Thi, Dieu Linh Tran, Xuyen Thi Vo   +11 more
openalex   +1 more source

Biosynthesis of hyaluronic acid in cultures of chondrocytes from the Swarm rat chondrosarcoma.

, 1982
Roger M. Mason, James H. Kimura, Vincent Hascall   +2 more
openalex   +1 more source