Results 291 to 300 of about 222,465 (345)

Tranexamic acid is toxic on human chondrocytes, in vitro

, 2019
Benjamin Jacob, Nadja Kloss, Sabrina Böhle, Julia Kirschberg, Timo Zippelius, Markus Heinecke, Georg Matziolis, Eric Röhner   +7 more
openalex   +2 more sources

Spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting restores physiological cartilage and subchondral bone properties in osteochondral knee defects ‐ An MRI‐based analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the radiological and patient‐reported outcome measures (PROMs) following spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting (MABCI) for the treatment of osteochondral defects of the knee.
Stephan Oehme, Benjamin Bartek, Janne Callsen, Jessica Schallock, Tobias Winkler, Thorsten Diekhoff, Tobias Jung, Danko Dan Milinkovic   +7 more
wiley   +1 more source

The crosstalk among macrophages, chondrocytes and mesenchymal stem cells in osteoarthritis: the role of extracellular vesicles. [PDF]

Stem Cell Res Ther
Kong H, Zheng J, Han J, Meng X, Li X, Wang X, Zhang XA.   +6 more
europepmc   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Developing Up-Scale Allogeneic Chondrocyte Therapies Using Juvenile Donor Cartilage. [PDF]

Int J Mol Sci
Hulme CH, Perry J, McCarthy HS, Lan T, Ranasinghe T, Kiely N, Freeman R, Wright J, Wright KT.   +8 more
europepmc   +1 more source

204 AN IKKα ASSOCIATED GENE EXPRESSION PROFILE IN DIFFERENTIATING CHONDROCYTES

, 2009
Eleonora Olivotto, Stefania Pagani, Annalisa Astolfi, Rosa Maria Borzı̀, Angelo Facchini, Flavio Flamigni, Angelo Facchini, Thomas Aigner, Mary B. Goldring, K.B. Marcu   +9 more
openalex   +1 more source

Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives We propose a non‐destructive laser method that uses controlled thermomechanical action to treat degenerative cartilage changes. The technique aims to reduce pain, offers a minimally invasive option for early‐ to mid‐stage degeneration, and lessens the need for joint replacement.
Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol   +6 more
wiley   +1 more source

Astragaloside IV Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis via the p53/SLC7A11/GPX4 Axis. [PDF]

J Inflamm Res
Tang Z, Cheng L, Li M, Chen J, Huang C.
europepmc   +1 more source

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

Macromolecular Materials and Engineering, EarlyView.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz, Sevda Gursoy, Gulsah Torkay, Shhd Saraj, Louna Karzoun, Alpay Kose, Mert Akin Insel, Ridvan Yildirim, Ayca Bal Ozturk, Ayse Ceren Calikoglu Koyuncu, Oguzhan Gunduz, Cem Bulent Ustundag   +11 more
wiley   +1 more source