Results 111 to 120 of about 22,928 (224)

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, Volume 46, Issue 8, Page 2884-2894, August 2026.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

Ontogeny and Homology of the Shoulder Joint and Forelimb Muscles in Frogs and Toads (Lissamphibia: Anura)

open access: yesJournal of Morphology, Volume 287, Issue 8, August 2026.
The ontogenetic development, innervation, and morphology of the shoulder joint and forelimb muscles were investigated in 11 anuran species. The results reveal largely conserved splitting patterns of the dorsal and ventral pre‐muscle masses, alongside interspecific variation in muscle subdivision and morphology.
Robin Saulnier Masson, Karolin Engelkes
wiley   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE‐A Cohort of 1.2 Million Surgeries

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen   +15 more
wiley   +1 more source

Revisiting Pluripotency Acquisition: A Unified Framework for Reprogramming Strategies

open access: yesDevelopment, Growth &Differentiation, Volume 68, Issue 6, August 2026.
ABSTRACT The traditional hierarchical view of totipotent cells generating diverse lineages of terminally differentiated cells was challenged by the discovery of induced pluripotent stem cells (iPSCs). This breakthrough demonstrated that the ectopic expression of four transcription factors, Oct4, Sox2, Klf4, and c‐Myc (OSKM), can reprogram somatic cells
Anamika Datta, Kunimasa Ohta
wiley   +1 more source

The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth

open access: yesOrthodontics &Craniofacial Research, Volume 29, Issue 4, Page 659-670, August 2026.
ABSTRACT Background The mid‐palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte‐derived osteogenesis to maxillary bone formation and the influence of ...
Michael Stark   +5 more
wiley   +1 more source

Species-specific roles of cellular communication network proteins in cartilage development: A comparative study using in vitro chondrogenic models. [PDF]

open access: yesJ Cell Commun Signal
Wang Z   +9 more
europepmc   +1 more source

Dichotomous SMAD2/3 regulation and selective antihypertrophic activity of heparin during in vitro chondrogenesis of mesenchymal stromal cells. [PDF]

open access: yesCell Mol Biol Lett
Schmidt S   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy