Results 91 to 100 of about 22,928 (224)

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases

Immunology &Cell Biology, EarlyView.
UCHL1‐associated pathology. The pathological role of UCHL1 in multisystem diseases, including cancer, neurological, musculoskeletal and cardiovascular disorders. ABSTRACT Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of ...
Ru Feng, Xiu Zhong, Jianjun Li, Adrian A. Achuthan   +3 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Secondary cartilage in the murine medial pterygoid plate has a critical role in the pathfinding of the tensor veli palatini

Journal of Anatomy, EarlyView.
The development of the medial pterygoid plate (MPP) is followed in mouse embryos, highlighting its neural crest origin and complex development via both endochondral and membranous ossification. Using transgenic mice, the secondary cartilage of the MPP is shown to direct the path of the tensor veli palatini.
Luke A. Barlow, Emi Nomura, Abigail S. Tucker   +2 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Report on the 13th international workshop on the CCN family of genes and inaugural ARBIOCOM conference, Nice, France

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Celebration of the 13th ICCNS meeting joint to the 1st ARBIOCOM Conference held on the site of Nice in December 2025. Abstract The 13th International Workshop on the CCN Family of Genes, held in Nice as part of the inaugural ARBIOCOM World Conference, brought together investigators with diverse research backgrounds, disciplines, and expertise. Building
Bernard Perbal, Ralf Weiskirchen, Annick Perbal, Brahim Chaqour   +3 more
wiley   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, Dmitriy Sheyn   +9 more
wiley   +1 more source

Network Model to Predict Age‐Related Transcriptional Reprogramming

Aging Cell, Volume 25, Issue 9, September 2026.
This study presents a network‐based model to predict intracellular responses to shifts in the extracellular environment and demonstrates the utility of the framework by estimating chondrocyte responses to age‐associated extracellular changes. Extracellular ligands are mapped to corresponding receptors, which serve as seed nodes for signal propagation ...
Tyler J. McNeill, Fabrisia Ambrosio, Hirotaka Iijima   +2 more
wiley   +1 more source

Intramuscular myxoma with chondroid features: two cases expanding the morphological spectrum

Histopathology, Volume 89, Issue 3, Page 554-557, September 2026.
Background Intramuscular myxoma is a benign mesenchymal tumour typically composed of bland spindle to stellate cells in abundant myxoid stroma and usually characterized by GNAS mutations. Chondroid matrix has not been previously reported in intramuscular myxoma.
Bethany Batson, Azfar Neyaz, Lucas Da Gama Lobo, Rana Naous, Stella J Lee, Ivy John   +5 more
wiley   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, Volume 28, Issue 16, 19 August 2026.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source