Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang +3 more
wiley +1 more source
Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties. [PDF]
Lorenzo NL +11 more
europepmc +1 more source
Chondrocyte‐targeted CS‐NAC nanoparticles restore redox balance, inhibit ferroptosis, and protect cartilage under mechanical stress. This nanoplatform enhances joint retention, elevates GPX4 activity, and attenuates osteoarthritis progression, offering a promising disease‐modifying therapeutic strategy.
Shaoyi Wang +8 more
wiley +1 more source
Protein catenation potentiates antitumor activity of malaria VAR2CSA navigation CAR-T cells in a mouse model of hematological malignancies. [PDF]
Hu W +12 more
europepmc +1 more source
Hydrogel Microspheres for Biomedical Applications
Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang +11 more
wiley +1 more source
Bone development of broiler chickens supplemented with chondroitin sulfate and manganese. [PDF]
Muñoz JA +9 more
europepmc +1 more source
Chondroitin / Dermatan Sulfate Modification Enzymes in Zebrafish Development
Judith Habicher +6 more
openalex +2 more sources
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Engineering of lipid membranes asymmetrically functionalized with chondroitin sulfate.
Rodríguez-García T +8 more
europepmc +1 more source

