Results 31 to 40 of about 86,202 (271)

Molecular Cloning of a Chondroitin Polymerizing Factor That Cooperates with Chondroitin Synthase for Chondroitin Polymerization [PDF]

open access: yesJournal of Biological Chemistry, 2003
We recently cloned human chondroitin synthase (ChSy) exhibiting the glucuronyltransferase-II (GlcATII) and N-acetylgalactosaminyltransferase-II (GalNAcTII) activities responsible for the biosynthesis of repeating disaccharide units of chondroitin sulfate, but chondroitin polymerization was not demonstrated in vitro using the recombinant ChSy. We report
Hiroshi, Kitagawa   +3 more
openaire   +2 more sources

大腸菌を用いたフォスファカン(コンドロイチン硫酸プロテオグリカン)の融合コア蛋白の発現条件の検討 [PDF]

open access: yes, 1996
Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

open access: yes, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi   +3 more
core   +1 more source

Preparation, Characterization and in Vitro Bioactivity of Chondroitin Sulfate Chelated Zinc

open access: yesShipin gongye ke-ji, 2022
In this paper, the preparation process condition of chondroitin sulfate chelated zinc was optimized by orthogonal test. Chondroitin sulfate and zinc sulfate were selected as the raw materials, chelating rate of zinc as evaluation index, the effects of pH,
Ran GAO   +3 more
doaj   +1 more source

Effectiveness of drugs with delayed-release structurally modified action depending on the phenotype of osteoarthritis

open access: yesМедицинский совет, 2020
Aim. To evaluate the effectiveness of a fixed combination of honadroitin and glucosamine sulfate (Teraflex, Bayer) in the treatment of osteoarthritis (OA), depending on the molecular phenotype of the disease.Materials and methods.
M. A. Kabalyk
doaj   +1 more source

Chondroitin Sulfate Alleviates Diabetic Osteoporosis and Repairs Bone Microstructure via Anti-Oxidation, Anti-Inflammation, and Regulating Bone Metabolism

open access: yesFrontiers in Endocrinology, 2021
Diabetic osteoporosis (DOP) belongs to secondary osteoporosis caused by diabetes; it has the characteristics of high morbidity and high disability. In the present study, we constructed a type 1 diabetic rat model and administered chondroitin sulfate (200
Shan Shan Qi   +17 more
doaj   +1 more source

Differential expression of ADAMTS -1, -4, -5 and TIMP -3 in rat spinal cord at different stages of acute experimental autoimmune encephalomyelitis [PDF]

open access: yes, 2005
Experimental autoimmune encephalomyelitis (EAE) is an animal model of inflammatory demyelination, a pathological event common to multiple sclerosis (MS). During CNS inflammation there are alterations in the extracellular matrix (ECM).
A.K. Cross   +52 more
core   +1 more source

Determinação espectroscópica multivariada de glucosamina e condroitina em formulações farmacêuticas Multivariate spectroscopic determination of glucosamine and chondroitin in pharmaceutical formulations

open access: yesQuímica Nova, 2008
The objective of this study was to develop and validate an analytical method for quantification of glucosamine and chondroitin in pharmaceutical formulations. Multivariate calibration combined with infrared spectrophotometry allowed this analysis.
Paula Rossignoli   +4 more
doaj   +1 more source

Simultaneous production of N-acetylheparosan and recombinant chondroitin using gene-engineered Escherichia coli K5

open access: yesHeliyon, 2023
N-Acetylheparosan and chondroitin are increasingly needed as alternative sources of animal-derived sulfated glycosaminoglycans (GAGs) and as inert substances in medical devices and pharmaceuticals. The N-acetylheparosan productivity of E.
Kiyoshi Suzuki, Hiromi Kaseyama-Takemoto
doaj   +1 more source

Glycosaminoglycans in the human cornea: age-related changes [PDF]

open access: yes, 2015
AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia   +6 more
core   +2 more sources

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