Results 51 to 60 of about 54,528 (266)

Influence of chondroitin 6-sulfate oligosaccharide unit addition on the immunopathogenicity of human thyroglobulin in cba/j(h-2k) mice. Multiple effects on antigen processing and t cell responses [PDF]

, 2006
The site of type D (chondroitin 6-sulfate) oligosaccharide unit addition to human thyroglobulin (hTg) was localized. Furthermore, hTg and its fractions endowed with chondroitin 6-sulfate oligosaccaride units (hTg-CS) and devoid of it (hTg-CS-), were ...
Conte, Marisa
core  

Transcribed var genes associated with placental malaria in Malawian women [PDF]

, 2006
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria vaccine.
Choong, Ee Ken, Boysen, Katja, Molyneux, Malcolm E, Caragounis, Aphrodite, Duffy, Michael F, Healer, Julie, Rowe, J Alexandra; id_orcid, Rogerson, Stephen J, Noviyanti, Rintis, Brown, Graham V, Kyriacou, Helen M   +10 more
core   +1 more source

Synergistic Chondroprotective Effect of α-Tocopherol, Ascorbic Acid, and Selenium as well as Glucosamine and Chondroitin on Oxidant Induced Cell Death and Inhibition of Matrix Metalloproteinase-3—Studies in Cultured Chondrocytes

Molecules, 2009
Overproduction of reactive oxygen species and impaired antioxidant defence accompanied by chronic inflammatory processes may impair joint health. Pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α) stimulate ...
Anne-Christi Graeser, Katri Giller, Heike Wiegand, Luca Barella, Christine Boesch Saadatmandi, Gerald Rimbach   +5 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

MEDICAL STUDIES ON CHONDROITIN SULFATE (1) [PDF]

, 1952
Chondroitin sulfate (daily 3g. per os) was administered to fifty cases of painful disorders, such as hemicrania, neuralgia, chronic rheumatoid arthritis, perialthritis, etc. And amelioration was observed in 34 cases (68%).
Oshima, Yoshio
core   +1 more source

Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]

PLoS ONE, 2014
The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz, Catherine M Willis, Toin H van Kuppevelt, Michael Klüppel   +3 more
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice

Journal of Alzheimer's Disease Reports, 2023
Background: Chondroitin sulfate and chondroitin sulfate proteoglycans have been associated with Alzheimer’s disease (AD), and the impact of modified chondroitin sulfates is being investigated in several animal and cell-based models of AD.
Sumit Bhattacharyya, Joanne K. Tobacman
doaj   +1 more source

Evaluation of mesalazine polymeric conjugate in the treatment of actinic proctitis in rats

Acta Cirúrgica Brasileira, 2021
Purpose: The present study aimed at testing a new formulation of mesalazine linked to chondroitin sulfate and its components alone in the treatment of actinic proctitis in rats.
Vinícius Rodrigues Taranto Nunes, Paula Vieira Teixeira Vidigal, Márcio Tadeu Pereira, Luís Carlos Duarte Ladeira, Marcelo Vidigal Caliari, Fabrício Marcus Silva Oliveira, Aina Liz Alves Cesar, André Augusto Gomes Faraco, Rafael Calvão Barbuto, Ivana Duval-Araujo   +9 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source