Results 61 to 70 of about 54,528 (266)

Critical appraisal of the role of glucosamine and chondroitin in the management of osteoarthritis of the knee [PDF]

open access: yes, 2010
Steven J Narvy1, C Thomas Vangsness Jr21Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; 2Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USAAbstract ...
Steven J Narvy, C Thomas Vangsness Jr
core  

MEDICAL STUDIES ON CHONDROITIN SULFATE (2nd Report) [PDF]

open access: yes, 1952
After the internal use of daily 3 grams of crude chondroitin sulfate cholinesterase activity of serum decreased and elimination of glycuronic acid in urine increased, but no definite change in serum mucoprotein level was observed.
Oshima, Yoshio, Yokota, Takeo
core   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

Chondroitin sulfate functionalized mesostructured silica nanoparticles as biocompatible carriers for drug delivery [PDF]

open access: yes, 2012
Juqun Xi,1 Jin Qin,2 Lei Fan21Department of Pharmacology, Yangzhou University Medical Academy, Yangzhou, People's Republic of China; 2School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, People's Republic of ...
Xi J, Qin J, Fan L
core   +1 more source

The clinical effectiveness of glucosamine and chondroitin supplements in slowing or arresting progression of osteoarthritis of the knee: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2009
Objective: To assess the clinical effectiveness and cost-effectiveness of glucosamine sulphate/hydrochloride and chondroitin sulphate in modifying the progression of osteoarthritis (OA) of the knee.
C Black   +7 more
doaj   +1 more source

Pharmacoeconomic analysis of various adjunctive pharmacotherapy strategies for back pain using comparative method

open access: yesМедицинский совет, 2018
Spinal disorders are one of the leading causes of disability worldwide. Back pain is one of the most important factors that reduce the patients’ quality of life.
P. A. Balunov
doaj   +1 more source

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

open access: yesAdvanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li   +7 more
wiley   +1 more source

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]

open access: yes, 2003
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Christodoulou, Z   +14 more
core   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen   +15 more
wiley   +1 more source

Glycosaminoglycans and vitamin C in ovo feeding affects bone characteristics of chicks

open access: yesRevista Brasileira de Zootecnia, 2018
Different levels of glycosaminoglycans (chondroitin sulfate and glucosamine sulfate) and vitamin C were injected in ovo to determine whether additive use influences the incubation parameters and bone characteristics of posthatch chicks.
Elaine Talita Santos   +7 more
doaj   +1 more source

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