Results 41 to 50 of about 60,461 (205)

Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in co-operation with chondroitin N-acetylgalactosaminyltransferase-2

, 2011
Previously, we demonstrated that sog9 cells, a murine L cell mutant, are deficient in the expression of C4ST (chondroitin 4-O-sulfotransferase)-1 and that they synthesize fewer and shorter CS (chondroitin sulfate) chains.
Toshiyasu Koike, Hiroshi Kitagawa, Yuka Okuura, Tomomi Izumikawa, Naoki Sakoda   +4 more
core   +1 more source

LITERATURE REVIEW ON GLUCOSAMINE AND CHONDROITIN IN OSTEOARTHRITIS TREATMENT

Tạp chí Khoa học
Osteoarthritis is a chronic disease primarily characterized by articular cartilage damage. In Vietnam, osteoarthritis accounts for a high percentage of musculoskeletal conditions, especially affecting the knee joints.
Dang Thi Soa*, Vu Thi Thuy, Nguyen Duc Trung, Bien Thi Thuc Uyen, Le Thi Hai Yen, Tran Trung Hieu, Tran Thao Linh
doaj   +1 more source

Synergistic Chondroprotective Effect of α-Tocopherol, Ascorbic Acid, and Selenium as well as Glucosamine and Chondroitin on Oxidant Induced Cell Death and Inhibition of Matrix Metalloproteinase-3—Studies in Cultured Chondrocytes

Molecules, 2009
Overproduction of reactive oxygen species and impaired antioxidant defence accompanied by chronic inflammatory processes may impair joint health. Pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α) stimulate ...
Anne-Christi Graeser, Katri Giller, Heike Wiegand, Luca Barella, Christine Boesch Saadatmandi, Gerald Rimbach   +5 more
doaj   +1 more source

Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice

Journal of Alzheimer's Disease Reports, 2023
Background: Chondroitin sulfate and chondroitin sulfate proteoglycans have been associated with Alzheimer’s disease (AD), and the impact of modified chondroitin sulfates is being investigated in several animal and cell-based models of AD.
Sumit Bhattacharyya, Joanne K. Tobacman
doaj   +1 more source

Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]

PLoS ONE, 2014
The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz, Catherine M Willis, Toin H van Kuppevelt, Michael Klüppel   +3 more
doaj   +1 more source

Evaluation of mesalazine polymeric conjugate in the treatment of actinic proctitis in rats

Acta Cirúrgica Brasileira, 2021
Purpose: The present study aimed at testing a new formulation of mesalazine linked to chondroitin sulfate and its components alone in the treatment of actinic proctitis in rats.
Vinícius Rodrigues Taranto Nunes, Paula Vieira Teixeira Vidigal, Márcio Tadeu Pereira, Luís Carlos Duarte Ladeira, Marcelo Vidigal Caliari, Fabrício Marcus Silva Oliveira, Aina Liz Alves Cesar, André Augusto Gomes Faraco, Rafael Calvão Barbuto, Ivana Duval-Araujo   +9 more
doaj   +1 more source

The clinical effectiveness of glucosamine and chondroitin supplements in slowing or arresting progression of osteoarthritis of the knee: a systematic review and economic evaluation

Health Technology Assessment, 2009
Objective: To assess the clinical effectiveness and cost-effectiveness of glucosamine sulphate/hydrochloride and chondroitin sulphate in modifying the progression of osteoarthritis (OA) of the knee.
C Black, C Clar, R Henderson, C MacEachern, P McNamee, Z Quayyum, P Royle, S Thomas   +7 more
doaj   +1 more source

Pharmacoeconomic analysis of various adjunctive pharmacotherapy strategies for back pain using comparative method

Медицинский совет, 2018
Spinal disorders are one of the leading causes of disability worldwide. Back pain is one of the most important factors that reduce the patients’ quality of life.
P. A. Balunov
doaj   +1 more source

Glycosaminoglycans and vitamin C in ovo feeding affects bone characteristics of chicks

Revista Brasileira de Zootecnia, 2018
Different levels of glycosaminoglycans (chondroitin sulfate and glucosamine sulfate) and vitamin C were injected in ovo to determine whether additive use influences the incubation parameters and bone characteristics of posthatch chicks.
Elaine Talita Santos, Sarah Sgavioli, Diana Maryuri Correa Castiblanco, Carla Heloísa de Faria Domingues, Thays Cristina Oliveira de Quadros, Liliana Longo Borges, Tiago Goulart Petrolli, Silvana Martinez Baraldi-Artoni   +7 more
doaj   +1 more source

DataSheet1_Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives.docx

, 2022
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate derivatives with specific length is always challenging.
Yang Wang (5921), Guocheng Du (390526), Ruirui Xu (483189), Weijiao Zhang (5943335), Xuerong Jin (11241928), Tianmeng Zhang (10201139), Zhen Kang (335450), Litao Hu (13036653)   +7 more
core   +1 more source