Results 161 to 170 of about 77,038 (354)
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core +1 more source
Viscosity and Turbidity of Mixed Solutions of Chondroitin Sulfate and Cationic Surface Active Agents
Masayuki Nakagaki, HARUKO KOKADO
openalex +2 more sources
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source
Impact of Immunosuppressive Drugs on Patients With Percutaneous Left Atrial Appendage Occlusion
ABSTRACT Introduction Percutaneous left atrial appendage closure (LAAC) reduces the risk of thromboembolic stroke in patients with non‐valvular atrial fibrillation who cannot tolerate long‐term oral anticoagulation. However, outcomes after LAAC in patients requiring chronic immunosuppressive therapy (IMS) remain unknown. This study aimed to investigate
Daisuke Togashi +7 more
wiley +1 more source
Rate of Chondroitin Sulfate Formation in Wound Healing
J. PETER BEKTLEY
openalex +2 more sources
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor +9 more
wiley +1 more source
The electrokinetic behavior of calcium oxalate monohydrate in macromolecular solutions [PDF]
Electrophoretic mobilities were measured for calcium oxalate monohydrate (COM) in solutions containing macromolecules. Two mucopolysaccharides (sodium heparin and chrondroitin sulfate) and two proteins (positively charged lysozyme and negatively charged ...
Curreri, P. A. +2 more
core +1 more source

