Results 11 to 20 of about 77,038 (354)
Neuroactive chondroitin sulfate glycomimetics [PDF]
Journal of the American Chemical Society, 2008 We report the generation of chondroitin sulfate (CS) glycomimetics with tunable chemical and biological properties. Our approach greatly simplifies the synthesis of complex glycosaminoglycans, providing synthetically accessible, bioactive structures of ...
Gama, Cristal I. +3 more
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CRYSTALLIZATION OF CALCIUM CHONDROITIN SULFATE [PDF]
Journal of Biological Chemistry, 1951 Julia M. Einbinder, Maxwell Schubert
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Biosynthesis of Chondroitin Sulfate
Journal of Biological Chemistry, 1969 Abstract A microsomal preparation from chick embryo cartilage has been shown to catalyze the incorporation of sulfate-35S from 3'-phosphoadenosine 5'-phosphosulfate-35S into microsomal glycosaminoglycan. This enzyme preparation is the same preparation that previously has been shown to catalyze the formation of chondroitin (nonsulfated) from sugar ...
J E Silbert, S DeLuca
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The Binding of Cations by Chondroitin Sulfate [PDF]
Journal of Clinical Investigation, 1957 Saul J. Färber, Maxwell Schubert
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THE OCCURRENCE OF INTRACELLULAR CHONDROITIN SULFATE [PDF]
The Journal of Cell Biology, 1963 Suspensions of chondrocytes were prepared by treatment with trypsin of the epiphyses of tibias and femurs of 13-day-old chick embryos. After washing to remove the matrix, such suspensions readily incorporate radioactive sulfate into both intracellular and extracellular chondroitin sulfate.
Frank K. Thorp, Albert Dorfman
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Chondroitin Sulfate and Fucosylated Chondroitin Sulfate as Stimulators of Hematopoiesis in Cyclophosphamide-Induced Mice [PDF]
Pharmaceuticals, 2021 The immunosuppression and inhibition of hematopoiesis are considered to be reasons for the development of complications after intensive chemotherapy and allogeneic hematopoietic stem cell transplantation. Chondroitin sulfate (CS), isolated from the fish Salmo salar, and fucosylated chondroitin sulfate (FCS), isolated from the sea cucumber Apostichopus ...
Nadezhda E. Ustyuzhanina +11 more
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Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]
PLoS ONE, 2014 The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz +3 more
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Chondroitin sulfate metabolism in the brain [PDF]
Acta Neurobiologiae Experimentalis, 2020 Over the last twenty years chondroitin sulfate (CS) has become a focus of interest of neuroscience due to its indubitable role in shaping axonal growth, synaptic plasticity and glial scar forming. Various patterns of sulfation give rise to various CS molecules with different properties that are capable of interactions with a plethora of molecules ...
Anna Katarzyna Greda, D Nowicka
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Molecules, 2021 Chondroitin sulfate is a proteoglycan component of the extracellular matrix (ECM) that supports neuronal and non-neuronal cell activity, provides a negative domain to the extracellular matrix, regulates the intracellular positive ion concentration, and ...
Shareen Singh +7 more
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Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A [PDF]
Carbohydrate Polymers, 2012 Chondroitin sulfate-E (chondroitin-4, 6-disulfate) was prepared from chondroitin sulfate-A (chondroitin-4 - sulfate) by regioselective sulfonation, performed using trimethylamine sulfur trioxide in formamide under argon. The structure of semi-synthetic chondroitin sulfate-E was analyzed by PAGE, (1)H NMR, (13)C NMR, 2D NMR and disaccharide analysis and
Amanda Weyers +6 more
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