Results 71 to 80 of about 64,099 (195)

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Extracellular matrix of the central nervous system: from neglect to challenge [PDF]

, 2018
The basic concept, that specialized extracellular matrices rich in hyaluronan, chondroitin sulfate proteoglycans (aggrecan, versican, neurocan, brevican, phosphacan), link proteins and tenascins (Tn-R, Tn-C) can regulate cellular migration and axonal ...
Dours-Zimmermann, María, Zimmermann, Dieter   +1 more
core  

Microfluidic Synthesis of Collagen‐Based Microgels for Tissue Engineering Applications

Nano Select, EarlyView.
We present a droplet microfluidic approach for preparing porous and irregularly shaped microgels of fibrillar collagen and collagen‐glycosaminoglycan (GAG) copolymer in a continuous oil phase at rates of up to 5500 s−1. ABSTRACT To expand the use of collagen‐based biomaterials beyond their current applications in three‐dimensional (3D) cell culture ...
Ehsan Samiei, Teodor Veres, Axel Günther   +2 more
wiley   +1 more source

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies [PDF]

, 2006
Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA ...
Ahmed Raza, Atalay, Baruch, Baruch, Buffet, Chen, Chen, Chitnis, Cohen, Cooke, Craig, Creasey, Fagan, Flick, Fried, Gamain, Gamain, Gardner, Guyatt, J. Alexandra Rowe, Jean-Philippe Semblat, Kyes, Kyes, Langone, Lin, Mayor, Medina, Medina, Rowe, Rowe, Rowe, Salanti, Salanti, Scholander, Smith, Smith, Su, Sue A. Kyes   +37 more
core   +1 more source

Bioactive and bactericidal biocomposites based on PBAT/PLA with hydroxyapatite and tannin derivative

Polymer Engineering &Science, EarlyView.
Preparation of biocomposites based on PBAT/PLA with hydroxyapatite and tannin derivative. Abstract The aim of this study was to develop innovative bioactive and bactericidal composites by enhancing the biodegradable Ecovio® blend, composed of poly(butylene adipate‐co‐terephthalate) (PBAT) and poly(lactic acid) (PLA), with hydroxyapatite (HA) and an ...
Ewerton de Oliveira Teotônio Bezerra, Samarah Vargas Harb, Leonardo Alves Pinto, Cesar Augusto Gonçalves Beatrice, Eduardo Henrique Backes, Lidiane Cristina Costa, Luiz Antonio Pessan   +6 more
wiley   +1 more source

From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism [PDF]

, 2009
Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatibility complex class II molecules.
Arora, Behrens, Bellocchio, Berthier, Bittencourt, Chang, Chevallet, Chevallet, Chieppa, Curtsinger, de Saint-Vis, Dillon, Elliott, Faure, Gallucci, Gharahdaghi, Goetz, Johnson, Jørgensen, Kawai, Kennedy, Levitz, Luche, Maldonado-López, Murray, Owhashi, Peng, Perkins, Porporatto, Rabilloud, Rabilloud, Rabilloud, Richert, Romani, Seong, Shibata, Tada, Termeer, Underhill, Verhasselt, Wang, Yang, Young   +42 more
core   +5 more sources

Diverse reactivity of maleimides in polymer science and beyond

Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick, Kristi S Anseth, Tayler S Hebner   +2 more
wiley   +1 more source

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Small Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri, Rodolfo Villa, Ya‐Ping Shiau, Menghuan Tang, Kelsey Jane Racacho, Qiufang Zong, Saiful Islam Chowdhury, Tan Hua, Felipe Godinez, Andrew Birkeland, Tzu‐Yin Lin, Yuanpei Li   +11 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source