Results 71 to 80 of about 77,038 (354)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Pathobiochemical pathways of redox imbalance in the neurological long-term effects of COVID-19 and the role of chondroitin sulfate in the redox status restoration

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
The review examines the epidemiology and clinical manifestations of COVID-19 long-term neurological effects, main pathobiochemical mechanisms, and integrated circuits of redox status impairment in COVID-19, such as the decrease of adenosine triphosphate ...
I. V. Sarvilina   +2 more
doaj   +1 more source

Autonomous Implants

open access: yesAdvanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda   +5 more
wiley   +1 more source

Effect of diclofenac sodium on the cartilage-regeneration potential of the chitosan-gelatin-chondroitin sulphate scaffold [PDF]

open access: yesIraqi Journal of Veterinary Sciences
Osteoarthritis (OA) is a joint disorder that results in decreased chondrocyte function, leading to degradation of the extracellular matrix. Tissue engineering, mainly using scaffolds as implants at the affected joints, has emerged as an effective way to ...
Aniek S. Budiatin   +5 more
doaj   +1 more source

Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer\u27s Disease [PDF]

open access: yes, 1993
Chondroitin sulfate proteoglycans (CSPG) are extracellular matrix proteins inhibitory to neurite outgrowth in vitro and correlated with decreased neurite outgrowth after CNS injury.
Canning, David R.   +3 more
core  

Permselectivity of the glomerular wall examined with iron compound tracer [PDF]

open access: yes, 1977
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core   +1 more source

Engineering Aging: Approaches to Model and Deconstruct Biological Complexity

open access: yesAdvanced Materials, EarlyView.
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar   +7 more
wiley   +1 more source

Biomedical Applications of Nanozymes: An Enzymology Perspective

open access: yesAngewandte Chemie, EarlyView.
With a lens of enzymology, this review compares nanozymes with enzymes using the Michaelis‐Menten model and differences in KM and kcat along with catalysis in complex biological environment. The implications of these differences in biomedical applications of nanozymes are then described with a statistical analysis of the trend of therapeutic use of ...
Vasily G. Panferov   +4 more
wiley   +2 more sources

Synthesis of heparosan oligosaccharides by Pasteurella multocida PmHS2 single-action transferases [PDF]

open access: yes, 2012
Pasteurella multocida heparosan synthase PmHS2 is a dual action glycosyltransferase that catalyzes the polymerization of heparosan polymers in a non-processive manner.
Boeriu, C.G.   +3 more
core   +2 more sources

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

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