Results 191 to 200 of about 15,622 (209)
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Journal of Leukocyte Biology, 1992
Abstract Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons. Following a 24-h incubation in the presence of [35S]sulfate and [3H]serine, total production and distribution of 35S-labeled proteoglycan into media (60–65%), pericellular (21–27%)
Rick T. Owens, William D. Wagner
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Abstract Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons. Following a 24-h incubation in the presence of [35S]sulfate and [3H]serine, total production and distribution of 35S-labeled proteoglycan into media (60–65%), pericellular (21–27%)
Rick T. Owens, William D. Wagner
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Isolation, Purification, and Analysis of Chondroitin Sulfate Proteoglycans
2006Publisher Summary This chapter discusses widely applicable procedures for the purification and characterization of chondroitin sulfate proteoglycans (CSPGs), using several typical CSPG species as examples. The purification of CSPGs is an essential step to determine the structure and function of CSPGs.
Atsuhiko Oohira, Fumiko Matsui
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Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding
Cell and Tissue Research, 1997This review focuses primarily on studies concerning the potential roles of two nervous-tissue-specific chondroitin sulfate proteoglycans, viz., neurocan and phosphacan, in cell interactions and neurite growth in the developing central nervous system.
Richard U. Margolis, Renée K. Margolis
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Expression of chondroitin sulfate proteoglycans in the chiasm of mouse embryos
The Journal of Comparative Neurology, 2000Chondroitin sulfate (CS) proteoglycans have been implicated as molecules that are involved in axon guidance in the developing neural pathways. The spatiotemporal expression of CS was investigated in the developing retinofugal pathway in mouse embryos by using the CS-56 antibody.
Shum, DKY, Chan, SO, Chung, KY
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Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma
2013The tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4) appears to be a useful biomarker to identify melanoma cells and an attractive target to apply antibody-based immunotherapy for the treatment of melanoma. Here we described the reverse transcription-polymerase chain reaction (RT-PCR) method and the immunohistochemical (IHC) staining method to ...
Wang, Yangyang +3 more
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Interaction of Proteoglycans and Chondroitin Sulfates with Calcium or Phosphate Ions
Canadian Journal of Biochemistry, 1971Equilibrium dialysis was used to study the distribution of calcium or phosphate ions at equilibrium in dialysis cells containing proteoglycan or chondroitin sulfate in one compartment. A higher concentration of calcium or lower concentration of phosphate was found in the cell compartment containing the polymer than in the compartment separated from it
J. M. Bowness, E. A. MacGregor
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Chondroitin sulfate proteoglycan of human leukocytes
Biochimica et Biophysica Acta (BBA) - General Subjects, 1969Abstract 1. 1. A chondroitin sulfate proteogylcan was isolated from leukocyte granules and partly characterized. It had a low protein content and a relatively low molecular size. 2. 2. The incorporation of [ 35 S]sulfate, [ 14 C]glucosamine and [ 3 H]serine into chondroitin sulfate was inhibited by puromycin, indicating that the elongation of
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Stimulation of Chondroitin Sulfate Proteoglycan Production by Chondrocytes in Monolayer
Connective Tissue Research, 1975Chondrocytes in monolayer undergo morphological and biochemical changes which culminate in the establishment of cartilage nodules in vitro. Chondroitin sulfate or heparin, added to the culture media of these cells, stimulates the production of chondroitin sulfate proteoglycan over the entire period of culture with a maximum effect during the log phase ...
Albert Dorfman, Nancy B. Schwartz
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Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination
Annals of Neurology, 2012AbstractObjective:Failure of remyelination is a critical impediment to recovery in multiple sclerosis (MS). Chondroitin sulfate proteoglycans (CSPGs) have been reported to accumulate in MS lesions, and we thus examined the functional roles of CSPGs on oligodendrocyte precursor cells (OPCs), oligodendrocytes, and remyelination.Methods:We evaluated the ...
V. Wee Yong +8 more
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The role of chondroitin sulfate proteoglycans in remyelination
2011Includes copy of animal protocol approval. Original copy with original Partial Copyright Licence.
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