Modulation of inflammation by chondroitin sulfate [PDF]
To evaluate the immune-modulator effect of chondroitin sulfate (CS) by means of the review of the literature.Inflammatory reactions are primarily originated by infectious agents, immune reactions and by sterile tissue lesions that activate membrane receptors by means of pathogen-associated molecular patterns, tissue breakdown products and cytokines ...
P. du Souich, M. Vallières
openaire +3 more sources
Demonstration of chondroitin sulfates degrading endo-β-glucuronidase activity in rabbit liver [PDF]
Reduced chondroitin sulfate was incubated with rabbit liver extracts followed by reduction once more with sodium [3H]borohydride, and then passed through a Sephadex G-100 column.
Takagaki, Keiichi+3 more
core +2 more sources
Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors [PDF]
Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Araujo, Mariana da Silva+7 more
core +1 more source
Antigenicity of Chondroitin Sulfate.
SummaryChondroitin sulfate extracted from human costal cartilage was prepared in 3 different ways for inoculation into rabbits, (1) a 1% solution, (2) a 1% solution incubated with heat-killed, group A, type 3, hemolytic streptococcus, and (3) a 1% solution incubated with heat-killed Staphylococcus aureus. These 3 preparations were injected into rabbits
Robert W. Quinn, Rose E. Cerroni
openaire +3 more sources
Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography [PDF]
Flavobacterium heparinum is a soil bacterium that produces several mucopolysaccharidases such as heparinase, heparitinases I and II, and chondroitinases AC, B, C and ABC. The purpose of the present study was to optimize the preparation of F.
Aguiar, Jair Adriano Kopke+1 more
core +1 more source
大腸菌を用いたフォスファカン(コンドロイチン硫酸プロテオグリカン)の融合コア蛋白の発現条件の検討 [PDF]
Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core +1 more source
Pharmacokinetic profile of glucosamine and chondroitin sulfate association in healthy male individuals [PDF]
Osteoarthrosis is a chronic joint disease that, once patent, leads to a progressive functional disability. As proteochondroitin sulfates are the major contents of the cartilage, it is expected that the ingestion of glucosamine and chondroitin might ...
Casarini, Dulce Elena+4 more
core +2 more sources
Technology and Properties of Chondroitin Sulfate from Marine Hydrobionts [PDF]
Chondroitin sulfate was isolated from the cartilage tissue of salmon (Salmo salar), northern skate (Raja hyperborean) and black-shark (Galeus melastomus). The polysaccharide content is from 67.1% to 82.2% in the samples.
Dolgopiatova, Nataliia+3 more
core +3 more sources
Specific inhibition of binding of antistasin and [A103,106,108] antistasin 93–119 to sulfatide (Gal(3-SO4)β1-1Cer) by glycosaminoglycans [PDF]
Leech-derived antistasin is a potent anticoagulant and antimetastatic protein that binds sulfatide (Gal(3-SO4)β1-1Cer)and sulfated polysaccharides. In this study, the synthetic fragment [A103,106,108] antistasin 93–119, which corresponds to the carboxyl ...
Brankamp, Robert G.+4 more
core +1 more source
Chondroitin Sulfate Safety and Quality [PDF]
The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals. CS possesses a heterogeneous structure and physical-chemical profile in different species and tissues, responsible for the various and more specialized functions of these macromolecules ...
openaire +3 more sources