Holothurian Fucosylated Chondroitin Sulfate [PDF]
Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within disaccharide repeating units as regularly found in mammalian chondroitin sulfates.
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Syndecan-1 regulates the biological activities of interleukin-34 [PDF]
IL-34 is a challenging cytokine sharing functional similarities with M-CSF through M-CSFR activation. It also plays a singular role that has recently been explained in the brain, through a binding to the receptor protein tyrosine phosphatase RPTPβ/ζ. The
Aude I. Segaliny+60 more
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Dimer-Promoted Fluorescence Quenching of Coralyne by Binding to Anionic Polysaccharides [PDF]
The effects of anionic chondroitin or dextran sulfates on the absorption and fluorescence properties of coralyne, a cationic benzo[c]phenanthridine type alkaloid, were studied in aqueous solution.
Baba+30 more
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Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan [PDF]
It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated.
Bellina, Isabella+11 more
core
Biomolecules that impact phenotypic transitions in fibroblasts and macrophages [PDF]
Macrophages and fibroblasts are intricately involved in many biological responses. The foreign body response (FBR) is orchestrated by macrophages, wherein the phenotypes of these macrophages exist plastically along a spectrum from M1, proinflammatory ...
Forsmark, Kiva Diane
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This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
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Catabolism of chondroitin sulfate
AbstractChondroitin sulfate (CS) is a ubiquitous component of the cell surface and extracellular matrix of animal tissues. CS chains are covalently bound to a core protein to form a proteoglycan, which is involved in various biological events including cell proliferation, migration, and invasion.
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THE OCCURRENCE OF INTRACELLULAR CHONDROITIN SULFATE [PDF]
Suspensions of chondrocytes were prepared by treatment with trypsin of the epiphyses of tibias and femurs of 13-day-old chick embryos. After washing to remove the matrix, such suspensions readily incorporate radioactive sulfate into both intracellular and extracellular chondroitin sulfate.
Frank K. Thorp, Albert Dorfman
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Materials Advances in Devices for Heart Disease Interventions
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra+11 more
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Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]
The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier+3 more
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