Results 11 to 20 of about 56,482 (307)

The diagnostic landscape of bone and soft tissue sarcoma: the pan-sarcoma era and AI-driven classification. [PDF]

open access: yesJ Pathol Clin Res
Abstract Bone and soft tissue sarcomas are a diagnostic challenge due to their histological complexity, variety, and mutational heterogeneity. This has led to continued refinements in classification and diagnostic criteria, presented and soon to be updated by the WHO.
Cross WC.
europepmc   +2 more sources

Mice with Trp53 and Rb1 deficiency in chondrocytes spontaneously develop chondrosarcoma via overactivation of YAP signaling

open access: yesCell Death and Disease, 2022
Chondrosarcoma (CHS) is a rare type of soft sarcoma with increased production of cartilage matrix arising from soft bone tissues. Currently, surgical resection is the primary clinical treatment for chondrosarcoma due to the poor response to radiotherapy ...
Yang Li   +3 more
doaj   +1 more source

Therapeutic Targets and Emerging Treatments in Advanced Chondrosarcoma

open access: yesInternational Journal of Molecular Sciences, 2022
Simple Summary Chondrosarcomas develop chemoresistance to standard anticancer drugs, making it difficult to control unresectable or metastatic chondrosarcomas. To improve the clinical outcomes of chondrosarcoma, new treatment approaches, such as molecule-
S. Miwa   +5 more
semanticscholar   +1 more source

WISP-3 Stimulates VEGF-C-Dependent Lymphangiogenesis in Human Chondrosarcoma Cells by Inhibiting miR-196a-3p Synthesis

open access: yesBiomedicines, 2021
Chondrosarcoma is a malignant bone tumor with high metastatic potential. Lymphangiogenesis is a critical biological step in cancer metastasis. WNT1-inducible signaling pathway protein 3 (WISP-3) regulates angiogenesis and facilitates chondrosarcoma ...
Chih-Yang Lin   +9 more
doaj   +1 more source

Chondrosarcoma-from Molecular Pathology to Novel Therapies

open access: yesCancers, 2021
Simple Summary Chondrosarcoma (CHS) belongs to a broad group of sarcomas and is the second most frequent malignant bone tumor. Due to its resistance to chemo- and radiotherapy, treatment of this tumor is complicated and is mainly limited to surgery.
Agnieszka E Zając   +10 more
semanticscholar   +1 more source

Mesenchymal chondrosarcoma of the mandible: A case report

open access: yesJournal of Craniomaxillofacial Research, 2021
Mesenchymal chondrosarcoma as an aggressive type of chondrosarcoma shows a characteristic biphasic histopathologic pattern. The head and neck region is included a high proportion of extra skeletal sites. Very rare examples of Mesenchymal Chondrosarcoma
Samira Derakhshan   +3 more
doaj   +1 more source

Clinical Statistical Analysis with Comparison between Pelvic and Non-pelvic Chondrosarcoma

open access: yesOman Medical Journal, 2021
Objectives: Chondrosarcomas are rare tumors with a variable biological characteristic. Their treatment clinically and surgically is controversial. Analysis of the clinical statistics and prognostic factors of pelvic chondrosarcoma provides a reference ...
Sayed Abdulla Jami   +4 more
doaj   +2 more sources

Visfatin-Induced Inhibition of miR-1264 Facilitates PDGF-C Synthesis in Chondrosarcoma Cells and Enhances Endothelial Progenitor Cell Angiogenesis

open access: yesCells, 2022
New treatments for chondrosarcoma are extremely important. Chondrosarcoma is a primary malignant bone tumor with a very unfavorable prognosis. High-grade chondrosarcoma has a high potential to metastasize to any organ in the body. Platelet-derived growth
Chang-Yu Song   +9 more
doaj   +1 more source

Testicular chondrosarcoma [PDF]

open access: yesInternational braz j urol, 2003
A case of primary chondrosarcoma of the testis is reported. A 40-year-old man presented a painless swelling of the right testis that he has been observing for 3 years. Gross examination of the resected specimen showed an encapsulated, gray to tan colored, roughly rounded tumor. Histologically, the tumor revealed a well-differentiated chondrosarcoma.
Yalçinkaya, Ulviye, Filiz, Gülaydan
openaire   +5 more sources

Prognostic importance of IDH mutations in chondrosarcoma: An individual patient data meta‐analysis

open access: yesCancer Medicine, 2021
IDH1/2 mutations are prevalent in cartilaginous tumors including chondrosarcoma. This meta‐analysis using individual patient data (IPD) aimed to investigate the clinical and prognostic association of these mutations in chondrosarcoma patients.
H. Vuong, T. Ngo, I. Dunn
semanticscholar   +1 more source

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