Results 21 to 30 of about 19,107 (247)
Chordoma is a relatively rare malignant bone tumor with high local recurrence. To date, the mechanism remains unclear. lncRNAs play a pivotal role in tumorigenesis by acting as competitive endogenous RNAs of microRNAs.
Kai Zhang +7 more
doaj +1 more source
Bibliometric analysis of the global research trends and hotspots in chordoma from 2000 to 2020
Introduction Chordoma is formed from embryonic residues or ectopic chordae and locally aggressive or malignant tumors. We visually analyzed the research tendency and hotspot of chordoma.
Cuicui Chang +4 more
doaj +3 more sources
Research hotspots and trends of chordoma: A bibliometric analysis
BackgroundChordoma is a type of mesenchymal malignancy with a high recurrence rate and poor prognosis. Due to its rarity, the tumorigenic mechanism and optimal therapeutic strategy are not well known.MethodsAll relevant articles of chordoma research from
Jianxuan Gao +6 more
doaj +1 more source
Dedifferentiated chordoma, a case report
Dedifferentiated chordoma is a rare variant of chordoma, exhibiting simultaneous presence of conventional chordoma and component of high grade sarcoma. It occurs either de novo or in the form of high grade transformation of a conventional chordoma in a ...
Girishma Shrestha +4 more
doaj +1 more source
Research Advances in Molecular Regulatory Mechanism of Chordoma
Chordoma is a rare primary malignant bone tumor derived from notochord remnants. Due to its strong local invasiveness and chemotherapy resistance, chordoma has a high local recurrence rate and poor prognosis.
LIANG Chen, YANG Chenlong, LIU Xiaoguang
doaj +1 more source
MicroRNA-155 expression is independently predictive of outcome in chordoma. [PDF]
BackgroundChordoma pathogenesis remains poorly understood. In this study, we aimed to evaluate the relationships between microRNA-155 (miR-155) expression and the clinicopathological features of chordoma patients, and to evaluate the functional role of ...
Choy, Edwin +9 more
core +3 more sources
Genotyping Cancer-Associated Genes in Chordoma Identifies Mutations in Oncogenes and Areas of Chromosomal Loss Involving CDKN2A, PTEN, and SMARCB1 [PDF]
The molecular mechanisms underlying chordoma pathogenesis are unknown. We therefore sought to identify novel mutations to better understand chordoma biology and to potentially identify therapeutic targets.
Choy, Edwin +9 more
core +8 more sources
Primary chordoma of the ethmoid sinus [PDF]
Primary chordoma of the paranasal sinuses are extremely rare tumours, with only a small number of cases verified and published in the literature. It appears that only five of these cases involved the ethmoid sinuses either as a primary or by local ...
Badia, L, Loughran, S, Lund, VJ
core +1 more source
Trigeminal nerve and pathologies in magnetic resonance imaging : a pictorial review [PDF]
A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the
Akgoz, Ayca +5 more
core +2 more sources
Background: Chordoma is a rare malignant bone tumor, and the survival prediction for patients with chordoma is difficult. The objective of this study was to construct and validate a nomogram for predicting cancer-specific survival (CSS) in patients with ...
Zhangheng Huang +3 more
doaj +1 more source

