Results 21 to 30 of about 19,107 (247)

LncRNA NONHSAT114552 Sponges miR-320d to Promote Proliferation and Invasion of Chordoma Through Upregulating NRP1

open access: yesFrontiers in Pharmacology, 2021
Chordoma is a relatively rare malignant bone tumor with high local recurrence. To date, the mechanism remains unclear. lncRNAs play a pivotal role in tumorigenesis by acting as competitive endogenous RNAs of microRNAs.
Kai Zhang   +7 more
doaj   +1 more source

Bibliometric analysis of the global research trends and hotspots in chordoma from 2000 to 2020

open access: yesPLoS ONE, 2022
Introduction Chordoma is formed from embryonic residues or ectopic chordae and locally aggressive or malignant tumors. We visually analyzed the research tendency and hotspot of chordoma.
Cuicui Chang   +4 more
doaj   +3 more sources

Research hotspots and trends of chordoma: A bibliometric analysis

open access: yesFrontiers in Oncology, 2022
BackgroundChordoma is a type of mesenchymal malignancy with a high recurrence rate and poor prognosis. Due to its rarity, the tumorigenic mechanism and optimal therapeutic strategy are not well known.MethodsAll relevant articles of chordoma research from
Jianxuan Gao   +6 more
doaj   +1 more source

Dedifferentiated chordoma, a case report

open access: yesJournal of Pathology of Nepal, 2022
Dedifferentiated chordoma is a rare variant of chordoma, exhibiting simultaneous presence of  conventional chordoma and component of high grade sarcoma. It occurs either de novo or in the form of high grade transformation of a conventional chordoma in a ...
Girishma Shrestha   +4 more
doaj   +1 more source

Research Advances in Molecular Regulatory Mechanism of Chordoma

open access: yesZhongliu Fangzhi Yanjiu, 2019
Chordoma is a rare primary malignant bone tumor derived from notochord remnants. Due to its strong local invasiveness and chemotherapy resistance, chordoma has a high local recurrence rate and poor prognosis.
LIANG Chen, YANG Chenlong, LIU Xiaoguang
doaj   +1 more source

MicroRNA-155 expression is independently predictive of outcome in chordoma. [PDF]

open access: yes, 2015
BackgroundChordoma pathogenesis remains poorly understood. In this study, we aimed to evaluate the relationships between microRNA-155 (miR-155) expression and the clinicopathological features of chordoma patients, and to evaluate the functional role of ...
Choy, Edwin   +9 more
core   +3 more sources

Genotyping Cancer-Associated Genes in Chordoma Identifies Mutations in Oncogenes and Areas of Chromosomal Loss Involving CDKN2A, PTEN, and SMARCB1 [PDF]

open access: yes, 2014
The molecular mechanisms underlying chordoma pathogenesis are unknown. We therefore sought to identify novel mutations to better understand chordoma biology and to potentially identify therapeutic targets.
Choy, Edwin   +9 more
core   +8 more sources

Primary chordoma of the ethmoid sinus [PDF]

open access: yes, 2000
Primary chordoma of the paranasal sinuses are extremely rare tumours, with only a small number of cases verified and published in the literature. It appears that only five of these cases involved the ethmoid sinuses either as a primary or by local ...
Badia, L, Loughran, S, Lund, VJ
core   +1 more source

Trigeminal nerve and pathologies in magnetic resonance imaging : a pictorial review [PDF]

open access: yes, 2018
A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the
Akgoz, Ayca   +5 more
core   +2 more sources

A Novel Nomogram for Predicting Cancer-Specific Survival in Patients With Spinal Chordoma: A Population-Based Analysis

open access: yesTechnology in Cancer Research & Treatment, 2021
Background: Chordoma is a rare malignant bone tumor, and the survival prediction for patients with chordoma is difficult. The objective of this study was to construct and validate a nomogram for predicting cancer-specific survival (CSS) in patients with ...
Zhangheng Huang   +3 more
doaj   +1 more source

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