Results 21 to 30 of about 19,276 (249)
Frontiers in Pharmacology, 2021 Chordoma is a relatively rare malignant bone tumor with high local recurrence. To date, the mechanism remains unclear. lncRNAs play a pivotal role in tumorigenesis by acting as competitive endogenous RNAs of microRNAs.
Kai Zhang +7 more
doaj +1 more source
Dedifferentiated chordoma, a case report
Journal of Pathology of Nepal, 2022 Dedifferentiated chordoma is a rare variant of chordoma, exhibiting simultaneous presence of conventional chordoma and component of high grade sarcoma. It occurs either de novo or in the form of high grade transformation of a conventional chordoma in a ...
Girishma Shrestha +4 more
doaj +1 more source
MicroRNA-155 expression is independently predictive of outcome in chordoma. [PDF]
, 2015 BackgroundChordoma pathogenesis remains poorly understood. In this study, we aimed to evaluate the relationships between microRNA-155 (miR-155) expression and the clinicopathological features of chordoma patients, and to evaluate the functional role of ...
Choy, Edwin +9 more
core +3 more sources
Research Advances in Molecular Regulatory Mechanism of Chordoma
Zhongliu Fangzhi Yanjiu, 2019 Chordoma is a rare primary malignant bone tumor derived from notochord remnants. Due to its strong local invasiveness and chemotherapy resistance, chordoma has a high local recurrence rate and poor prognosis.
LIANG Chen, YANG Chenlong, LIU Xiaoguang
doaj +1 more source
Primary chordoma of the ethmoid sinus [PDF]
, 2000 Primary chordoma of the paranasal sinuses are extremely rare tumours, with only a small number of cases verified and published in the literature. It appears that only five of these cases involved the ethmoid sinuses either as a primary or by local ...
Badia, L, Loughran, S, Lund, VJ
core +1 more source
Trigeminal nerve and pathologies in magnetic resonance imaging : a pictorial review [PDF]
, 2018 A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the
Akgoz, Ayca +5 more
core +2 more sources
Technology in Cancer Research & Treatment, 2021 Background: Chordoma is a rare malignant bone tumor, and the survival prediction for patients with chordoma is difficult. The objective of this study was to construct and validate a nomogram for predicting cancer-specific survival (CSS) in patients with ...
Zhangheng Huang +3 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundChordoma, an extremely rare malignant tumor, remains difficult to be cured because of its strong local invasiveness and high recurrence rate. Long non-coding RNAs (lncRNAs) have been demonstrated to play multiple roles in various cancers.
Kai Zhang +10 more
doaj +1 more source
Spotlight on zebrafish:translational impact [PDF]
, 2014 In recent years, the zebrafish has emerged as an increasingly prominent model in biomedical research. To showcase the translational impact of the model across multiple disease areas, Disease Models & Mechanisms has compiled a Special Issue that includes ...
Amatruda, James F +3 more
core +2 more sources
Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines. [PDF]
, 2014 OBJECT: Chordoma cells can generate solid-like tumors in xenograft models that express some molecular characteristics of the parent tumor, including positivity for brachyury and cytokeratins. However, there is a dearth of molecular markers that relate to
Alcorta, David A +10 more
core +1 more source