Results 41 to 50 of about 7,766 (184)

Bibliometric Insights in Advances of Chordoma: Global Trends and Research Development in the Last Decade

open access: yesOrthopaedic Surgery, 2023
Chordoma is a rare tumor, but has a serious effect on the quality of life of patients. This study aims to assess the overall knowledge structure and trends in the development of chordoma research using a bibliometric analysis and visualization tool ...
Yu Xiao   +7 more
doaj   +1 more source

Fluid-fluid level as an atypical radiological sign of clival chordoma

open access: yesRadiology Case Reports, 2021
Chordoma is a rare and aggressive intracranial bone tumor that is difficult to diagnose and resect with a peak incident between the ages of 20–40 years old and high recurrence rate when not completely resected.
Fahad B. Albadr   +2 more
doaj   +1 more source

Vascular Control‐Focused Surgical Strategy for Pterygopalatine and Infratemporal Fossa Tumors Using Multimodal Image Fusion Reconstruction

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To classify tumor–internal maxillary artery (IMA) spatial relationships in pterygopalatine and infratemporal fossa (PPF/ITF) tumors, develop a 3D fusion–guided vascular control‐focused surgical strategy, and evaluate its clinical impact.
Zi‐Cheng He   +5 more
wiley   +1 more source

Low expression of H3K27me3 is associated with poor prognosis in conventional chordoma

open access: yesFrontiers in Oncology, 2022
PurposeChordoma is a rare and locally invasive neoplasm, and the prognostic factors are limited. Deregulation of Histone 3 lysine 27 (H3K27) trimethylation (H3K27me3) is considered to be related with poor prognosis in some tumors.
Jie Wei   +9 more
doaj   +1 more source

Intraspinal chordomas [PDF]

open access: yesSpinal Cord, 1987
Intraspinal chordomas are rare tumors, comprising about 1% of central nervous system tumors. They are derived from notochordal elements which have failed to degenerate and are mainly found in the sphenooccipital and sacrococcygeal regions. These tumors are very slowly growing, are virtually impossible to excise completely and only metastasise in about ...
openaire   +2 more sources

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

open access: yesCytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu   +3 more
wiley   +1 more source

Human eosinophils exert antitumorigenic effects on chordoma

open access: yesChinese Neurosurgical Journal
Background Chordoma is a devastating rare tumor with a poor prognosis, limited therapeutic options and a high recurrence rate. The exploration of novel therapeutic targets has important clinical significance in chordoma diagnosis, treatment, and outcome ...
Wang Ying   +6 more
doaj   +1 more source

Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish

open access: yesDisease Models & Mechanisms, 2019
The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants.
Gianluca D'Agati   +8 more
doaj   +1 more source

Chordoma.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
The history, origin, pathology, diagnosis, treatment and prognosis of chordoma involving the axial skeleton are reviewed, and the clinical histories of 3 cases of chordoma are given, noting some remarkable features, along with one case misdiagnosed as chordoma on the radiological appearance of the sacrum and treated as such, which later proved to be a ...
Fichardt, T., de Villiers, P.C.
openaire   +3 more sources

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

open access: yesHistopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori   +5 more
wiley   +1 more source

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