Results 21 to 30 of about 16,071 (223)

PALB2 as a factor to predict the prognosis of patients with skull base chordoma

Frontiers in Oncology, 2022
ObjectiveThis study aimed to study the role of PALB2 on the prognosis of skull base chordoma patients and the proliferation, migration, and invasion of chordoma cells.
Yujia Xiong, Mingxuan Li, Yutao Shen, Tianshun Ma, Jiwei Bai, Yazhuo Zhang, Yazhuo Zhang, Yazhuo Zhang, Yazhuo Zhang   +8 more
doaj   +1 more source

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

Prognostic Significance of Cyclin E1 Expression in Patients With Chordoma: A Clinicopathological and Immunohistochemical Study

Frontiers in Oncology, 2020
PurposeChordomas are rare, slow-growing sarcomas without any accepted prognostic biomarkers. Owing to their proximity to critical neurovascular structures, discovering predictive biomarkers in chordoma has been a significant research effort because it ...
Ran Wei, Ran Wei, Dylan C. Dean, Pichaya Thanindratarn, Pichaya Thanindratarn, Francis J. Hornicek, Wei Guo, Zhenfeng Duan   +7 more
doaj   +1 more source

Comparison of Oncologic Outcomes and Treatment-Related Toxicity of Carbon Ion Radiotherapy and En Bloc Resection for Sacral Chordoma

JAMA Network Open, 2022
Key Points Question How do the outcomes of carbon ion radiotherapy (CIRT) compare with the outcomes obtained with en bloc surgical resection for sacral chordoma?
Y. Yolcu, Jad Zreik, W. Wahood, A. Bhatti, M. Bydon, M. Houdek, P. Rose, A. Mahajan, I. Petersen, M. Haddock, Safia K. Ahmed, N. Laack, K. Jethwa, E. Jeans, R. Imai, S. Yamada, R. Foote   +16 more
semanticscholar   +1 more source

A Rare Chordoma-The Epiglottic chordoma

Ear, Nose & Throat Journal, 2022
Chordomas are rare malignant bone tumors. Chordomas originate from notochordal elements. Chordomas have the phenotype of the embryonic notochord, characterized by the dual expression of cytokeratin and brachyury. Chordomas occur anywhere along the central axis. Rarely, chordomas occur in extra-axial structures.
Jinfen Yu, Linsheng Wang, Nan Jiang, Chuanting Li, Lixin Sun   +4 more
openaire   +2 more sources

Gluteus maximus metastasis from sacrococcygeal chordoma: A case report

Radiology Case Reports, 2022
We reported the metastatic chordoma in the right gluteus maximus of a 73-year-old man. The patient was initially diagnosed with sacrococcygeal chordoma and treated with surgical resection.
Wanchen Liu, MD, Xiao Xu, MD, Zhongsheng Zhang, MD, Jian Sun, MD, Heng Ma, MD   +4 more
doaj   +1 more source

MRI-Based Radiomics Differentiates Skull Base Chordoma and Chondrosarcoma: A Preliminary Study

Cancers, 2022
Simple Summary In this study, we created a novel MRI-based machine learning model to differentiate skull base chordoma and chondrosarcoma with multiparametric signatures.
Erika Yamazawa, Satoshi Takahashi, M. Shin, Shota Tanaka, W. Takahashi, T. Nakamoto, Yuichi Suzuki, Hirokazu Takami, N. Saito   +8 more
semanticscholar   +1 more source

Gene expression profiling identifies two chordoma subtypes associated with distinct molecular mechanisms and clinical outcomes

Clinical Cancer Research, 2022
Purpose: Chordoma is a rare bone tumor with a high recurrence rate and limited treatment options. The aim of this study was to identify molecular subtypes of chordoma that may improve clinical management.
J. Bai, Jianxin Shi, Yazhuo Zhang, Chuzhong Li, Yujia Xiong, H. Koka, Difei Wang, Tongwu Zhang, Lei Song, W. Luo, B. Zhu, B. Hicks, A. Hutchinson, Erin L Kirk, M. Troester, Mingxuan Li, Yutao Shen, Tengyu Ma, Junmei Wang, Xing Liu, Shuai Wang, S. Gui, M. McMaster, S. Chanock, D. Parry, A. Goldstein, Xiaohong R. Yang   +26 more
semanticscholar   +1 more source

Dedifferentiated chordoma, a case report

Journal of Pathology of Nepal, 2022
Dedifferentiated chordoma is a rare variant of chordoma, exhibiting simultaneous presence of  conventional chordoma and component of high grade sarcoma. It occurs either de novo or in the form of high grade transformation of a conventional chordoma in a ...
Girishma Shrestha, Paromita Roy, Indu Arun, Argha Chatterjee, Gautam Biswas   +4 more
doaj   +1 more source

Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1-Mutated Human Chordoma Xenograft

Cancers, 2022
Simple Summary Chordomas are rare bone tumors characterized by a high recurrence rate. Presently, no medical treatment is available for advanced diseases due to the lack of molecular data and preclinical models. The current study showed the establishment
T. Passeri, A. Dahmani, J. Masliah-Planchon, A. Naguez, Marine Michou, Rania El Botty, S. Vacher, Rachida Bouarich, A. Nicolas, M. Polivka, C. Franck, Anne Schnitzler, F. Némati, S. Roman-Roman, F. Bourdeaut, H. Adle-Biassette, H. Mammar, S. Froelich, I. Bièche, D. Decaudin   +19 more
semanticscholar   +1 more source