Results 41 to 50 of about 7,206 (161)
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
P. Fenech +8 more
wiley +1 more source
Fluid-fluid level as an atypical radiological sign of clival chordoma
Chordoma is a rare and aggressive intracranial bone tumor that is difficult to diagnose and resect with a peak incident between the ages of 20–40 years old and high recurrence rate when not completely resected.
Fahad B. Albadr +2 more
doaj +1 more source
Immunohistochemical expression of CD34, desmin, keratin AE1/AE3, keratin 8/18, KIT, SMA, S100, and vimentin in normal guinea pig skin serving as both positive and negative external tissue control. All images immunohistochemical staining, 200× magnification, scale bar 100 µm. (A) CD34 stained only vascular endothelium (arrow).
Jiří Lenz +3 more
wiley +1 more source
Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants.
Gianluca D'Agati +8 more
doaj +1 more source
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin +12 more
wiley +1 more source
Abstract Objective Dosiomics and radiomics elaborate the low‐and high‐order features extracted from images to predict clinical outcomes. Whole‐brain radiotherapy (WBRT) has been widely used in patients with diffuse brain metastases of small cell lung cancer (SCLC).
Yifan Lei +11 more
wiley +1 more source
Function and regulation of miR-186-5p, miR-125b-5p and miR-1260a in chordoma
Background The function and regulation of miRNAs in progression of chordoma were unclear. Methods Five miRNAs were identified by the machine learning method from the miRNA expression array. CCk-8 assay, EDU assay, wound healing migration assay, and trans-
Xulei Huo +9 more
doaj +1 more source
Radiogenomics: Current Understandings and Future Perspectives
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang +8 more
wiley +1 more source
ABSTRACT Background Here we report the results of the first comprehensive European trials for all soft tissue sarcoma entities, which aimed to develop a new risk stratification system, limit radiotherapy and chemotherapy for low‐/standard‐risk patients, and evaluate different chemotherapy regimens for high‐risk patients.
Amadeus T. Heinz +16 more
wiley +1 more source
ABSTRACT Background Cancer survivors often receive inadequate pain management, leading to impaired quality of life. Despite their importance, evidence on the global prevalence of chronic pain in cancer survivors remains insufficiently clear. Aims The systematic review and proportional meta‐analysis aimed to estimate the pooled global prevalence of ...
Pak Kit Wong +3 more
wiley +1 more source

