Results 51 to 60 of about 19,107 (247)

Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma

Photodiagnosis and Photodynamic Therapy
Background: Chordoma is a rare congenital low-grade malignant tumor characterized by infiltrative growth. It often tends to compress important intracranial nerves and blood vessels, making its surgical treatment extremely difficult. Besides, the efficacy
Lei Li, Kai-lun Wei, Ming-song Liu, Qi-lin Wang, Tong-fei Zeng, Rui-zhe Chen, Xue-wei Xia, Hong-tian Zhang   +7 more
doaj   +1 more source

In-room test results at CNAO of an innovative PT treatments online monitor (Dose Profiler) [PDF]

, 2018
The use of C, He and O ions as projectiles in Particle Therapy (PT) treatments is getting more and more widespread as a consequence of their enhanced relative biological effectiveness and oxygen enhancement ratio, when compared to the protons one.
Battistoni G., De Simoni M., Dong Y., Embriaco A., Fischetti M., Mancini Terracciano C., Marafini M., Mattei I., Mirabelli R., Muraro S., Patera V., Sarti A., Schiavi A., Sciubba A., Solfaroli Camillocci E., Traini G., Valle S. M.   +16 more
core   +1 more source

Children and Adolescents With Localised Non‐Rhabdomyosarcoma Soft Tissue Sarcoma: Results of the CWS‐96 and CWS‐2002P Prospective Trials With Reclassification of the Trial Data Incorporating the Recent Soft Tissue Sarcoma Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Here we report the results of the first comprehensive European trials for all soft tissue sarcoma entities, which aimed to develop a new risk stratification system, limit radiotherapy and chemotherapy for low‐/standard‐risk patients, and evaluate different chemotherapy regimens for high‐risk patients.
Amadeus T. Heinz, Anton Schönstein, Ewa Koscielniak, Martin Ebinger, Jörg Fuchs, Semi Harrabi, Christian Vokuhl, Roland Imle, Sabine Stegmaier, Ines B. Brecht, Gustaf Ljungman, Hanna Juntti, Ruth Ladenstein, Bernarda Kazanowska, Thomas Klingebiel, Kristian W. Pajtler, Monika Sparber‐Sauer   +16 more
wiley   +1 more source

Potential molecular mechanism in self-renewal is associated with miRNA dysregulation in sacral chordoma – A next-generation RNA sequencing study

Heliyon, 2022
Background: Chordoma, the most frequent malignant primary spinal neoplasm, characterized by a high rate of recurrence, is an orphan disease where the clarification of the molecular oncogenesis would be crucial to developing new, effective therapies ...
Arpad Bozsodi, Beata Scholtz, Gergo Papp, Zoltan Sapi, Adam Biczo, Peter Pal Varga, Aron Lazary   +6 more
doaj   +1 more source

Intracranial chordoma presenting as acute hemorrhage in a child: Case report and literature review [PDF]

, 2015
BACKGROUND: Chordomas are rare, slow-growing malignant neoplasms derived from remnants of the embryological notochord. Pediatric cases comprise only 5% of all chordomas, but more than half of the reported pediatric chordomas are intracranial.
Abdulkader, Marwah M., Ackerman, Laurie L., Bohnstedt, Bradley N., Bonnin, Jose M., Kralik, Stephen F., Moore, Kenneth A., Shah, Mitesh V., Shah, Sanket U., Shaikh, Kashif   +8 more
core   +2 more sources

Early Initiation of Adjuvant Therapy Following Pediatric Endoscopic Endonasal Surgery for Tumors

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate complication rates of early adjuvant therapy initiation in pediatric patients with endoscopic endonasal resection for skull base tumors. Design Retrospective case series of pediatric patients (0–18 years old) with skull base tumors who underwent endoscopic endonasal resection between 2013 and 2023.
Heta Patel, Alan D. Workman, David K. Lerner, Phillip J. Storm, Jennifer E. Douglas, Nithin D. Adappa, James N. Palmer, Michael A. Kohanski   +7 more
wiley   +1 more source

Long Non-Coding RNA KCNQ1OT1 Promotes Multidrug Resistance in Chordoma by Functioning as a Molecular Sponge of miR-27b-3p and Subsequently Increasing ATF2 Expression

Cancer Management and Research, 2020
Lei Li, Guohua Lv, Bing Wang, Hong Ma Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, People’s Republic of ChinaCorrespondence: Hong Ma Tel +86 731-85295124Email spinema@csu.edu ...
Li L, Lv G, Wang B, Ma H
doaj  

Perineal chordoma cutis, a rare localization for a rare pathology: a case report and consideration of the literature

PAMJ Clinical Medicine, 2020
The chordoma is a very rare notochordal tumor, the cutaneous localization (chordoma cutis) is even rarer and generally follows a local invasion of the integument even a metastasis. The clinical presentation is non-specific and the diagnosis is often late.
Chennoufi Mehdi, Mhanna Tarik, Irzi Mohamed, Jdaini Ahmed, Boukhannous Ibrahim, Barki Ali   +5 more
doaj   +1 more source

Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis [PDF]

, 2016
Dedifferentiated chondrosarcoma (DDCS) is a rare disease with a dismal prognosis. DDCS consists of two morphologically distinct components: the cartilaginous and noncartilaginous components.
Cao, Dengfeng, Chen, Rongrong, Chen, Xi, DeLaney, Thomas F, Gao, Lu, Gao, Xiaohuan, Gong, Xinqi, Guo, Xiaopeng, Hong, Xiafei, Ni, Jianjiao, Tian, Pangzehuan, Wang, Renzhi, Xing, Bing, Yao, Yong   +13 more
core   +2 more sources

Ependymoma and Chordoma

Neurosurgery, 2020
Abstract Ependymoma and chordoma are 2 tumors that occur throughout the craniospinal axis, and for which the extent of neurosurgical resection has a key prognostic role. Both tumors have distinctive pathologic features, yet can present significant diagnostic challenges to pathologists in cases without classical histology.
Adrian B Levine, Derek Wong, Mostafa Fatehi, Stephen Yip   +3 more
openaire   +2 more sources