RARE-30. PEDIATRIC GLIOBLASTOMA IN THE POST-TEMOZOLOMIDE ERA: OUTCOMES AND CHARACTERISTICS [PDF]
, 2019 INTRODUCTION Glioblastoma (GBM) is the most common brain tumor, however, is a rare occurrence in children and is poorly characterized. We evaluated the characteristics and outcomes of pediatric GBM (pGBM).
Aghi, Manish +7 more
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The 'incidentaloma' of the pituitary gland. Is neurosurgery required? [PDF]
, 1990 We describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5 to 25 mm.
Allolio, Bruno +4 more
core +1 more source
Radiogenomics: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 2, February 2026.Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang +8 more
wiley +1 more source
Fluid-fluid level as an atypical radiological sign of clival chordoma
Radiology Case Reports, 2021 Chordoma is a rare and aggressive intracranial bone tumor that is difficult to diagnose and resect with a peak incident between the ages of 20–40 years old and high recurrence rate when not completely resected.
Fahad B. Albadr +2 more
doaj +1 more source
Indium(111) pentetreotide single photon emission computed tomography (In-111 pentetreotide SPECT): a new technique to evaluate somatostatin receptors in chordomas [PDF]
, 2005 Chordomas are rare neoplasms originating along the neuraxis. Although they do not usually show cytological atypia, metastases have been reported in 30 per cent of cases.
Bruno, E +5 more
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Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.ABSTRACT Background Here we report the results of the first comprehensive European trials for all soft tissue sarcoma entities, which aimed to develop a new risk stratification system, limit radiotherapy and chemotherapy for low‐/standard‐risk patients, and evaluate different chemotherapy regimens for high‐risk patients.
Amadeus T. Heinz +16 more
wiley +1 more source
Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
Disease Models & Mechanisms, 2019 The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants.
Gianluca D'Agati +8 more
doaj +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Function and regulation of miR-186-5p, miR-125b-5p and miR-1260a in chordoma
BMC Cancer, 2023 Background The function and regulation of miRNAs in progression of chordoma were unclear. Methods Five miRNAs were identified by the machine learning method from the miRNA expression array. CCk-8 assay, EDU assay, wound healing migration assay, and trans-
Xulei Huo +9 more
doaj +1 more source
Spontaneous intracranial hypotension : two steroid-responsive cases [PDF]
, 2018 Purpose: Spontaneous intracranial hypotension (SIH) is characterised by orthostatic headache, low cerebrospinal fluid pressure and diffuse pachymeningeal enhancement after intravenous gadolinium contrast administration.
Alexis, Zandolino +5 more
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